High-Field Multinuclear NMR In Undergraduate Education at Washington and Lee University

华盛顿与李大学本科教育中的高场多核核磁共振

• 批准号: 9650033
• 负责人: Erich Uffelman
• 金额: $ 9.95万
• 依托单位: Washington and Lee University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-06-01 至 1998-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9650033&HistoricalAwards=false
• 关键词: Field; Multinuclear; NMR; Undergraduate; Education

This project supports development of a series of undergraduate experiments involving high-field nuclear magnetic resonance (NMR). These new experiments are being employed throughout the curriculum, ranging from general chemistry to undergraduate research. Many of the experiments are designed to make links between courses. For example, in collaboration with the Waymouth group at Stanford, a suite of experiments for undergraduates involving new oscillating Ziegler-Natta polymerization catalysts is being implemented. This experiment begins in organic chemistry with the synthesis of ligands and concludes in inorganic chemistry with the synthesis of the catalyst and the study of the polymerization process. Similarly, cross-disciplinary experiments are being developed involving porphyrin synthesis, spectroscopic characterization, and metallation. Routine use of 1H NMR becomes possible in the large organic class, and regular use of 13C NMR and two-dimensional NMR techniques is possible in the spectroscopy class. Pre-existing undergraduate research programs in synthesis, catalysis, and protein structure can flourish with the acquisition of the new high-field NMR, and new research initiatives in polymer chemistry are being made possible. The new experiments currently under development, as well as those being planned, can be disseminated in the educational literature as laboratory manuals and journal articles, as well as presented at conferences. Research results may generate both student and faculty presentations at conferences and scholarly papers in the chemical literature.

该项目支持一系列涉及高场核磁共振（NMR）的本科实验的开发。这些新实验正在整个课程中使用，从普通化学到本科研究。许多实验的目的是使课程之间的联系。例如，与斯坦福大学的Waymouth小组合作，正在为大学生实施一套涉及新型振荡齐格勒-纳塔聚合催化剂的实验。本实验从有机化学中配体的合成开始，以无机化学中催化剂的合成和聚合过程的研究结束。 类似地，正在开发涉及卟啉合成、光谱表征和代谢的跨学科实验。常规使用1H NMR在大有机类中成为可能，并且常规使用13 C NMR和二维NMR技术在光谱类中成为可能。现有的合成，催化和蛋白质结构的本科生研究计划可以蓬勃发展与新的高场NMR的收购，并在聚合物化学新的研究计划正在成为可能。 目前正在开发和计划中的新实验可以作为实验室手册和期刊文章在教育文献中传播，也可以在会议上介绍。研究结果可能会在会议上产生学生和教师的报告，并在化学文献中产生学术论文。