Advanced Experimental Methods: An Integrated Approach

先进的实验方法：综合方法

• 批准号: 8852353
• 负责人: Marc Walters
• 金额: $ 3.82万
• 依托单位: New York University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-12-01 至 1991-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8852353&HistoricalAwards=false
• 关键词: Advanced; Experimental; Methods; Integrated; Approach

This project is designed to meet the needs of new interdisciplinary approaches at the interface of physical, bio-, and inorganic chemistry. The proposed experiments are designed specifically to introduce the techniques and style of modern chemical research as it is applied to molecules of proven biological relevance. For this purpose model systems have been chosen and include porphyrin and metalloporphyrin compounds which have been intensively studied and have rich chemical properties in liganding, catalysis, electron transfer, and oxygen transport. Further, the well documented and rationalized spectroscopic properties of these compounds make them ideal for laboratory instruction. Students will use several techniques including absorption, fluorescence, IR, NMR and ESR spectroscopy to characterize the structure, binding, and redox properties of these molecules. This ILI award from the Chemistry Shared Instrumentation Program will help the Department of Chemistry at New York University to acquire UV/VIS and IR spectrometers, fluorescence spectrometer accessories, and four PC's for data acquisition, digitization and manipulation. Upgrades for a fluorimeter, NMR and ESR instruments are also supported by the award. The instrumentation will be used to enhance undergraduate laboratory instruction and impact on chemistry curriculum development.

该项目旨在满足物理、生物和无机化学交叉领域新的跨学科方法的需求。 所提出的实验专门设计用于介绍现代化学研究的技术和风格，因为它应用于已证明具有生物相关性的分子。 为此目的，选择了模型系统，包括卟啉和金属卟啉化合物，这些化合物经过深入研究，在配体、催化、电子转移和氧传输方面具有丰富的化学性质。 此外，这些化合物的详细记录和合理化的光谱特性使其成为实验室教学的理想选择。 学生将使用吸收、荧光、红外、核磁共振和 ESR 光谱等多种技术来表征这些分子的结构、结合和氧化还原特性。 化学共享仪器计划颁发的 ILI 奖项将帮助纽约大学化学系购买紫外/可见光和红外光谱仪、荧光光谱仪配件以及四台用于数据采集、数字化和操作的 PC。 该奖项还支持荧光计、NMR 和 ESR 仪器的升级。 该仪器将用于加强本科生实验室教学以及对化学课程开发的影响。