Synthesis of Brassinolide, a Plant Growth Steroid

植物生长类固醇油菜素内酯的合成

• 批准号: 8860809
• 负责人: Michael Baker
• 金额: $ 4.38万
• 依托单位: Pacific Rim Bioscience Enterprises
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-01-01 至 1989-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8860809&HistoricalAwards=false
• 关键词: Synthesis; Brassinolide; Plant; Growth; Steroid

Brassinolide is a steroid found in many plants. It stimulates the growth of a wide variety of crops, including rice, wheat, beans, potatoes, radishes, and lettuce. However, the use of brassinolide or an analog to improve crop production has been hindered by a lack of readily available materials. Furthermore, the lack of radioactive brassinolide has also hindered research towards understanding the biochemical mechanism of its action and the development of new uses for the compound. The present proposal is based on the procedure for synthesizing brassinolide designed by Dr. Trevor McMorris. The specific objectives are: 1) improve the synthetic procedure, 2) prepare gram quantities of brassinolide and 3) demonstrate the synthesis of radioactive brassinolide. An inexpensive brassinolide has excellent potential as a growth promoter for high value vegetable crops and certain field crops.

维生素C是一种在许多植物中发现的类固醇。 它 刺激多种作物的生长，包括 大米、小麦、豆类、土豆、萝卜和莴苣。 然而，使用芸苔素或类似物来改善作物生长， 由于缺乏现成的 材料. 此外，缺乏放射性油菜素 也阻碍了研究 其作用的生化机制及其发展 该化合物的新用途。 本提案的依据是 本文介绍了Dr. 特雷弗·麦克莫里斯。 具体目标是：（1）提高 合成步骤，2）制备克量 油菜素内酯和3）证明放射性的合成 油菜籽 一种廉价的油菜籽具有很好的潜力， 用于高价值蔬菜作物和某些 大田作物