Catalysis and Mechanism in Nucleophilic Aromatic Photo- substitution

有机动力学项目的续期拨款为格林内尔学院的Gene Wubbels博士的研究提供了支持。该项目将招收六名主修有机合成、光化学、反应产物的分离和表征以及反应动力学测量的本科生，并将在一个设备齐全的非研究生系进行，该系一直是化学博士学位的重要学士学位来源。本研究的主题是均相光化学反应的催化作用和亲核芳香光取代的机理。该研究将继续探索光化学催化的新课题，通过确定Bronsted催化定律图的性质，获得涉及氢氧根离子的电子空穴转移催化的明确证据，并阐明碱催化与猝灭竞争的结构要求。阐明了分子内氢在芳环上光取代的中间结构，并首次测量了亲核芳环光取代的“元素效应”。

This renewal grant in the Organic Dynamics Program provides support for the research of Dr. Gene Wubbels of Grinnell College. The project will engage six undergraduates in organic synthesis, photochemistry, isolation and characterization of reaction products and measurement of reaction kinetics and will take place in a well-equipped, non-graduate department that has been a significant baccalaureate source of Ph.D.'s in chemistry. The theme of the research is catalysis of homogeneous photochemical reactions and mechanisms of nucleophilic aromatic photosubstitution. The research will continue to explore the novel subject of catalysis in photochemistry by determining the nature of Bronsted Catalysis Law plots, obtaining definitive evidence for electron hole transfer catalysis involving hydroxide ion, and elucidating the structural requirements governing a case in which base catalysis competes with quenching. Intermediate structures involved in intramolecular photodisplacement of hydrogen on an aromatic ring will be elucidated and the "element effect" on nucleophilic aromatic photosubstitution will be measured for the first time.