Catalysis and Mechanism in Nucleophilic Aromatic Photo- substitution

亲核芳香光取代的催化及机理

• 批准号: 8902378
• 负责人: James Swartz
• 金额: $ 4.35万
• 依托单位: Grinnell College
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-06-01 至 1991-11-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8902378&HistoricalAwards=false
• 关键词: Catalysis; Mechanism; Nucleophilic; Aromatic; Photo

This renewal grant in the Organic Dynamics Program provides support for the research of Dr. Gene Wubbels of Grinnell College. The project will engage six undergraduates in organic synthesis, photochemistry, isolation and characterization of reaction products and measurement of reaction kinetics and will take place in a well-equipped, non-graduate department that has been a significant baccalaureate source of Ph.D.'s in chemistry. The theme of the research is catalysis of homogeneous photochemical reactions and mechanisms of nucleophilic aromatic photosubstitution. The research will continue to explore the novel subject of catalysis in photochemistry by determining the nature of Bronsted Catalysis Law plots, obtaining definitive evidence for electron hole transfer catalysis involving hydroxide ion, and elucidating the structural requirements governing a case in which base catalysis competes with quenching. Intermediate structures involved in intramolecular photodisplacement of hydrogen on an aromatic ring will be elucidated and the "element effect" on nucleophilic aromatic photosubstitution will be measured for the first time.

有机动力学计划的更新补助金提供 支持格林内尔的吉恩·沃贝尔斯博士的研究 学院该项目将聘请六名本科生在有机 合成、光化学、分离和表征 反应产物和反应动力学的测量， 发生在一个设备齐全，非研究生部门， 是博士学位的重要来源。里有 化学.本研究的主题是催化剂 均相光化学反应及其机理 亲核芳族光取代 本研究将继续探索新的主题， 光化学中的催化作用 布朗斯台德催化定律图，获得明确的证据， 涉及氢氧根离子的电子空穴转移催化，和 阐明案件的结构要求， 碱催化与猝灭竞争。中间 参与分子内光致位移的结构 将阐明芳环上的氢， 芳香亲核光取代反应中的“元素效应” 将首次被测量。