RUI: The Physiology of Maternal-Fetal Relations in Developing Elasmobranchs

RUI：软骨鱼发育过程中母胎关系的生理学

• 批准号: 8904429
• 负责人: Gregg Kormanik
• 金额: $ 14.07万
• 依托单位: University of North Carolina at Asheville
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-08-01 至 1993-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8904429&HistoricalAwards=false
• 关键词: RUI; Physiology; Maternal; Fetal; Relations

This project will examine the physiology of the maternal-fetal relationship in developing embryos. The elasmobranchs (sharks, skates and rays) are used since they represent a relatively simple system compared to the more complex mammals and humans. The mother, to varying degrees, provides oxygen and nutrients as well as for the removal of wastes for embryos developing in the uterus. This study will promote a better understanding of the movements of oxygen and carbon dioxide between the mother and embryo, and the mechanisms by which these gases move across tissues in general. Nitrogenous wastes accumulate in the fluids bathing the embryo, and must be eliminated. The manner by which waste products such as ammonia and urea are detoxified and transported will be better understood. Lastly, salts are also regulated by the mother, until the embryo may regulate for itself. The role of the various organs involved in the regulation of salt (kidney, gills and rectal gland) will be described as well as the mechanisms by which salt is transported across tissues. The information gained in this study will be used to provide a model to describe the physiology of the maternal-fetal relationship.

这个项目将研究母胎的生理学 与胚胎发育的关系 板鳃类（鲨鱼，冰鞋 和射线），因为它们表示相对简单的系统 与更复杂的哺乳动物和人类相比。 母亲，以不同的 度，提供氧气和营养物质，以及去除 胚胎在子宫内发育的废物。 这项研究将促进 更好地了解氧气和二氧化碳的运动 母亲和胚胎之间的联系，以及这些气体 在组织间移动。 含氮废物积聚在 液体沐浴胚胎，必须被排除。 以何种方式 氨和尿素等废物被解毒并运输 会被更好地理解。 最后，盐也受《 母亲，直到胚胎可以自己调节。 的作用 参与盐调节的各种器官（肾脏、鳃和 直肠腺）将被描述，以及盐的机制， 是通过组织运输的 本研究中获得的信息 将被用来提供一个模型来描述的生理 母胎关系