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Novel strategies to enhance efficiency of nucleoside analog drug uptake: Endocytosis of equilibrative nucleoside transporter 1 upon substrate binding and ultrasound-microbubble mediated delivery of nucleoside analog drugs

Novel strategies to enhance efficiency of nucleoside analog drug uptake: Endocytosis of equilibrative nucleoside transporter 1 upon substrate binding and ultrasound-microbubble mediated delivery of nucleoside analog drugs
提高核苷类似物药物摄取效率的新策略：底物结合时平衡核苷转运蛋白 1 的内吞作用和超声微泡介导的核苷类似物药物递送
批准号：
311840
负责人：
Zafar Maliha
金额：
$1.27万
依托单位：
Toronto Metropolitan University
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2013
资助国家：
加拿大
项目状态：
已结题
起止时间：
2013-12-01 至 2014-12-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=311840&lang=en
关键词：
Cancer Therapy Cell Biology Clathrin Mediated Endocytosis Gemcitabine Hent1 Membrane Protein Nucleoside Analog Drug Nucleoside Transporter Pharmacology Ultrasound-Microbubble

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The focus of my research is understanding structure, function and regulation of membrane proteins. I am currently studying the regulation of the equilibrative nucleoside transporter, ENT1, which is responsible for the flux of nucleosides and nucleoside an
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