Comparing Genetic Variation Patterns Among Tamarin Species (Saguinus)

比较狨猴物种（Saguinus）的遗传变异模式

• 批准号: 8906041
• 负责人: James Cheverud
• 金额: $ 19.9万
• 依托单位: Washington University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-10-15 至 1993-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8906041&HistoricalAwards=false
• 关键词: Comparing; Genetic; Variation; Patterns; Among

Dr. Cheverud will measure patterns of heritable variation and covariation in the size and shape of the face in two tamarin species, the saddle-back tamarin (Saguinus fuscicollis) and the endangered cotton-top tamarin (S.oedipus), to determine the relative stability of inheritance patterns across these closely related species and the extent to which interspecific differences in facial size and shape are consistent with the inherited pattern. These results will be important in evaluating the genetic basis for evolutionary change in tamarins generally, and also specifically in the endangered cotton-top tamarin. Dr. Cheverud will also examine the extent to which the pattern of facial character inheritance and co-inheritance is consistent with patterns of facial growth. Do characters which are under the influence of the same growth factors tend to be inherited together? In this study, concepts from quantitative genetics and systematics are fused to form the groundwork for future studies in which it may be possible to reconstruct the selective forces responsible for facial size and shape evolution in tamarins. The study populations consist of skeletons obtained over the past 15 years through normal attrition from the Oak Ridge Associated Universities" (ORAU) Marmoset Research Center. Detailed demographic records, including age-at-death and genealogical relationship are available for these specimens providing a rare opportunity for genetic studies on primates. The three-dimensional coordinates of facial landmarks will be recorded and used in a finite-element scaling analysis of facial size and shape. The numerical results of this analysis will be used in a quantitative genetic study of inheritance and co- inheritance of facial features. Patterns of heritable variation will be compared between species and to growth relations using randomization statistical procedures. This study will be unique in bringing together new techniques and concepts in quantitative genetics, morphometrics, and statistics for the study of evolutionary systematics.

Cheverud博士将测量遗传变异的模式 和脸的大小和形状的协变 种，鞍背绢毛猴（Saguinus fuscicollis）和 濒危棉顶绒猴（S.俄狄浦斯），以确定 继承模式的相对稳定性， 相关物种和种间差异程度 面部大小和形状与遗传的 格局 这些结果将是重要的评估 一般说来，绢毛猴进化变化的遗传基础，以及 尤其是濒危的棉顶绢毛猴。 博士 Cheverud还将研究在多大程度上， 面部特征遗传与共遗传一致 面部生长的模式。 做的字符是根据 相同生长因子的影响往往是遗传的， 一起吗？ 在这项研究中，来自数量遗传学和 系统学的融合形成了未来研究的基础 在这个过程中，我们有可能重建选择力， 负责绢毛猴面部大小和形状的进化。 研究人群包括在整个研究期间获得的骨骼。 在过去的15年里，从橡树岭的正常消耗， 联合大学（ORAU）绒猴研究中心。 详细的人口统计记录，包括死亡年龄和 对这些标本进行了系谱分析 为灵长类动物的遗传学研究提供了难得的机会。 面部标志的三维坐标将是 记录并用于面部的有限元缩放分析 大小和形状。 该分析的数值结果将是 用于遗传和共同遗传的定量遗传学研究， 面部特征的遗传 遗传变异模式 将比较物种之间和生长关系， 随机化统计程序。 这项研究将是独一无二的 将新的技术和概念结合在一起， 遗传学、形态学和统计学， 进化系统学