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Targeting microglia-synapse interactions to rescue from brain circuits elimination and cognitive dysfunction

Targeting microglia-synapse interactions to rescue from brain circuits elimination and cognitive dysfunction
针对小胶质细胞-突触相互作用来挽救脑回路消除和认知功能障碍
批准号：
333623
负责人：
Tremblay Marie-Ève
金额：
$69.48万
依托单位：
CHU de Qubec
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2015
资助国家：
加拿大
项目状态：
已结题
起止时间：
2015-09-01 至 2020-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=333623&lang=en
关键词：
3d-Scanning Electron Microscopy Aging Alzheimer'S Disease Chronic Stress Cognitive Decline Microglia-Synapse Interactions Neuronal Activity Super-Resolution Microscopy Synaptic Loss Two-Photon In Vivo Imaging

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中文摘要
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英文摘要
A series of discoveries spanning the last six years has challenged our view of microglia, the brain's immune cells, showing their essential but previously unexpected contribution to the experience-dependent remodeling of neuronal circuits. In this nascent
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Canada Resaerch Chair - Tier 2
Canada Research Chair Tier 2
  • 批准号：
    373615
  • 项目类别：
  • 资助金额：
    $36.43万
  • 财政年份：
    2016
  • 负责人：
    Tremblay Marie-Ève
  • 依托单位：
    Universit Laval
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