Solvatochromic Studies of Solvated Surface Phases

溶剂化表面相的溶剂化变色研究

• 批准号: 8921315
• 负责人: Sarah Rutan
• 金额: $ 15.9万
• 依托单位: Virginia Commonwealth University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-04-15 至 1994-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8921315&HistoricalAwards=false
• 关键词: Solvatochromic; Studies; Solvated; Surface; Phases

This grant is in the general field of analytical and surface chemistry and in the subfield of separations science. Professor Sarah Rutan will study the structure of stationary phases used in liquid chromatography. By using a combination of optical spectroscopy of molecular probes in specific solvent environments she will determine the so-called solvatochromic parameters of the system. From this approach the fundamental structure and reactivity of the molecular species at the liquid solid interface can be determined. A better understanding of the mechanisms of molecular interactions which give rise to separations of molecular species in flow will result. Molecular interactions between probe molecules and liquid chromatographic stationary phases will be determined. Optical (uv-visible and infrared spectroscopic band shifts will be measured and analyzed to remove solution phase interferences. Dipolarity-polarizability, hydrogen bond acidity and basicity will allow an understanding of solvent based reactivity and adsorption effects underlying separations and other liquid solid interfacial systems. The particular solvent systems will include methanol, acetonitrile and tetrahydrofuran - water mixtures commonly used in high performance liquid chromatography. Hydrocarbon and phenyl modified silica as well as unmodified silica will be studied. The probe molecules include a series of nitroaniline dyes commonly used to probe solvent solute interactions. Unique capabilities to perform multicomponent analysis and eliminate the contributions of liquid phase effects will allow improvement over the current level of understanding of the dynamics of adsorption at the molecular level in solution.

该资助属于分析和表面化学的一般领域以及分离科学的子领域。 Sarah Rutan 教授将研究液相色谱中使用的固定相的结构。 通过在特定溶剂环境中结合使用分子探针的光谱，她将确定系统的所谓溶剂化变色参数。 通过这种方法，可以确定液固界面处分子种类的基本结构和反应性。 将更好地理解导致流动中分子种类分离的分子相互作用机制。 将确定探针分子和液相色谱固定相之间的分子相互作用。 将测量和分析光学（紫外-可见光和红外光谱带位移）以消除溶液相干扰。偶极性-极化性、氢键酸度和碱度将有助于了解分离和其他液固界面系统中基于溶剂的反应性和吸附效应。特定的溶剂系统将包括甲醇、乙腈和四氢呋喃-水混合物 常用于高效液相色谱。 将研究烃和苯基改性二氧化硅以及未改性二氧化硅。 探针分子包括一系列通常用于探测溶剂溶质相互作用的硝基苯胺染料。 执行多组分分析和消除液相效应影响的独特功能将提高目前对溶液中分子水平吸附动力学的理解水平。