Solvatochromic Studies of Solvated Surface Phases

这项资助是在一般领域的分析和表面 化学和分离科学的子领域。 萨拉·鲁坦教授将研究静止的 液相色谱法中使用的相。 通过使用组合 分子探针在特定溶剂中的光谱学 环境中，她将确定所谓的溶致变色 系统的参数。 从这个角度来看， 分子种类在液体中的结构和反应性 可以确定固体界面。 更好地了解 分子间相互作用的机制， 将导致流中分子种类的分离。 探针分子与液体间的分子相互作用 将确定色谱固定相。 光学 （紫外可见和红外光谱带位移将是 测量并分析以除去溶液相干扰。 偶极性-极化率、氢键酸碱性 将允许理解基于溶剂的反应性， 分离和其他液体的吸附效应 固体界面系统 特定的溶剂体系将 包括甲醇、乙腈和四氢呋喃-水 高性能液体中常用的混合物 层析 烃和苯基改性二氧化硅以及 因为将研究未改性的二氧化硅。 探针分子 包括一系列通常用于探测 溶剂-溶质相互作用 独特的性能 多组分分析和消除的贡献 液相效应将允许改进电流 对吸附动力学的理解水平 溶液中的分子水平。

This grant is in the general field of analytical and surface chemistry and in the subfield of separations science. Professor Sarah Rutan will study the structure of stationary phases used in liquid chromatography. By using a combination of optical spectroscopy of molecular probes in specific solvent environments she will determine the so-called solvatochromic parameters of the system. From this approach the fundamental structure and reactivity of the molecular species at the liquid solid interface can be determined. A better understanding of the mechanisms of molecular interactions which give rise to separations of molecular species in flow will result. Molecular interactions between probe molecules and liquid chromatographic stationary phases will be determined. Optical (uv-visible and infrared spectroscopic band shifts will be measured and analyzed to remove solution phase interferences. Dipolarity-polarizability, hydrogen bond acidity and basicity will allow an understanding of solvent based reactivity and adsorption effects underlying separations and other liquid solid interfacial systems. The particular solvent systems will include methanol, acetonitrile and tetrahydrofuran - water mixtures commonly used in high performance liquid chromatography. Hydrocarbon and phenyl modified silica as well as unmodified silica will be studied. The probe molecules include a series of nitroaniline dyes commonly used to probe solvent solute interactions. Unique capabilities to perform multicomponent analysis and eliminate the contributions of liquid phase effects will allow improvement over the current level of understanding of the dynamics of adsorption at the molecular level in solution.