Presidential Young Investigators Award

该研究奖的最终目标是提高 机械理解，建立理论基础 或有意义的测量，并提供合理的基础， 选择性调节细胞运动性以优化 细胞功能化学物质诱导细胞运动 身体上的暗示对很多问题都至关重要， 生物医学和生物技术是变形和 周围纤维基质的重组， 潜在的细胞牵引力。 表征 这些特性并了解它们 在体内的后果是统一的主题接近使用 细胞行为测定结合数学 单细胞和细胞群/连续体模型 程度.

The ultimate goals of this research award are to enhance the mechanistic understanding, establish theoretical foundations or meaningful measurements, and provide a rational basis for selectively modulating cell motility for optimizing celfunction. Directed cell movements in response to chemical and physical cues are crucial to many problems in biomedicine and biotechnology as are the deformation and restructuring of the surrounding fibrous matrix due to underlying cell tractional forces. Characterization of these properties in vitro and understanding their consequences in vivo are unifying themes approached using cell behavior assays in conjunction with mathematical models at both the single cell and cell population/continuum levels.