Development of the Genetic Map of Volvox

团藻carteri是一个潜在的强大的模式，用于分析 细胞分化和形态发生的遗传控制。 每一个个体都含有两种完全不同的细胞类型， 在植物人和 生殖功能，并且以高度规则的方式排列， 在一个简单的椭圆体中。 因为生物体是单倍体 并在无性周期中迅速繁殖，个体拥有 影响关键发育过程的突变很容易 孤立的，并成长为大的，遗传上同质的， 人口数量。 但是因为生物体可以从无性 对有性生殖的意愿，正式的遗传分析也是 可能 我们的目标是绘制出 团藻对未来的发育和分子遗传学更有用 研究，将其扩展到包括其他耐药性 限制性片段长度多态性， 重排断点。 作为向阐明 调节生殖细胞分化的遗传程序 细胞，我们将尝试识别和映射所有的基因座， 突变要么导致劳动分工的瓦解 体细胞和生殖细胞之间，或导致组成性 有性生殖 团藻在单细胞披衣细胞之间架起了差距的桥梁， 多细胞高等植物 因此团藻的基础研究 在进化和发展研究中很重要。**//

Volvox carteri is a potentially powerful model for analyzing the genetic control of cellular differentiation and morphogenesis. Each individual contains two entirely different cell types that exhibit a complete division of labor between vegetative and reproductive functions, and that are arranged in a highly regular pattern within a simple spheroid. Because the organism is haploid and reproduces rapidly in the asexual cycle, individuals possessing mutations affecting key developmental processes are readily isolated, and grown into large, genetically homogeneous populations. But because the organism can be switched from asexual to sexual reproduction at will, formal genetic analysis is also possible. Our objective is to make the genetic linkage map of Volvox more useful for future developmental- and molecular-genetic studies, by extending it to include additional drug-resistance markers, restriction fragment length polymorphisms and rearrangement breakpoints. And, as a major step toward elucidating the genetic programs that regulate differentiation of reproductive cells, we will attempt to identify and map all of the loci at which mutations either result in a breakdown of the division of labor between somatic and reproductive cells, or result in constitutive sexual reproduction. Volvox bridges the gap between single-celled chlamydomonas, and multicellular higher plants. Therefore, basic studies of Volvox are important in evolutionary and developmental studies.***//