Configural Association Theory and Hippocampal Function in Learning and Memory

配置联想理论与海马学习记忆功能

• 批准号: 9008251
• 负责人: Jerry Rudy
• 金额: $ 2万
• 依托单位: University of Colorado at Boulder
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-08-01 至 1992-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9008251&HistoricalAwards=false
• 关键词: Configural; Association; Theory; Hippocampal; Function

The PI seeks support for an investigation of a novel theory to investigate the role of the hippocampus in learning and memory. Specifically, that the hippocampal formation provides the neural substrates that enables an animal to construct a representation of the joint occurance of two or more stimulus elements. An important point of this theory is that it allows the explanation of how animals can solve problems that require non-linear solutions. In another words, it allows animals to solve problems that cannot be solved by a learning system that simply algebraically sums the associative strengths of the individual cues that compose a stimulus. This is an interesting proposal by an innovative and highly productive investigator. The proposed research is a gamble and there is a minimum of preliminary data to allow an easy judgement. However, the investigator has made excellent progress and is now at a stage of his research where a definitive decision on the validity of the configural association theory can be made. The potential for a significant outcome seems sufficient to justify the risk. This work has the potential to move behavioral neuroscience significantly closer to an understanding of the neural systems that underlie learning and memory.

PI寻求对一种新理论的研究的支持 研究海马体在学习中的作用， 记忆 具体来说，海马结构提供了 使动物能够构建 两个或多个刺激的联合出现的表示 元素 这个理论的一个重要观点是， 解释动物如何解决需要 非线性解决方案。 换句话说，它允许动物 解决学习系统无法解决的问题， 简单地代数求和的关联强度的 构成刺激的单个线索。 这是一个有趣 这是一位富有创新精神和高效率的调查员提出的建议。 拟议中的研究是一场赌博， 初步的数据，以便于判断。 但 调查人员取得了很大进展，目前正处于 在他的研究中， 可以建立结构联想理论。 的可能性 结果似乎足以证明风险是合理的。 这 这项工作有可能将行为神经科学 我们对神经系统的理解 是学习和记忆的基础