A Role for Serotonin in the Control of Sympathetic Nerve Activity

这项建议是研究一个特定的神经的作用， 脑干的脊髓和髓质中的通路 交感神经系统的控制。 唯一性 PI可以识别特定的神经元， 通过两种化学标识符的途径。 一些途径包含 5-羟色胺和一些含有促甲状腺激素释放激素（TRH） 但只有一种途径同时包含这两种物质， 这些发射器的路径可以被识别， 定义了 这项研究将大大提高我们对 对大脑控制交感神经系统的理解。

This proposal is to study the role of a specific neural pathway in the spinal cord and medulla of the brainstem in the control of the sympathetic nervous system. The uniqueness of this proposal is that the PI can identify a specific neural pathway by two chemical identifiers. Some pathways contain serotonin and some contain thyrotropin releasing hormone (TRH) but only one pathway contains both and it is by the combined use of these transmitters that the pathway can be recognized and defined. The study should add greatly to the accuracy of our understanding of brain control of the sympathetic nervous system.