Central integration of Inhibitory Inputs Modulating Autonomic Components of Defensive Behavior

环境挑战从压力到威胁生命不等，动物必须对它们做出反应才能生存。典型的防御反应包括恐惧，这涉及心率和血压的增加，以逃避肌肉准备帮助动物逃离威胁。 人类对这些具有挑战性的情况产生类似的反应。神经系统组织反应。当动物面临威胁时，神经会发出信息提醒大脑，大脑又会向需要做出反应的组织和器官发送信息。神经细胞使用称为神经递质的化学物质传递信息，研究人员将研究特定的神经递质如何在大脑神经接头处相互作用，以产生正确的防御反应。为此，研究人员将使用电生理学和神经药理学方法。 这项研究对于帮助我们理解神经信号处理非常重要，并且可以为我们提供一种可以应用于大脑许多功能的机制。该项目还将为本科生和研究生提供生理学培训机会，并将在小学一级进行演讲，以鼓励对科学的兴趣。

Environmental challenges vary from stressful to life-threatening and animals must respond to them for survival. Typical defensive responses range from fear, which involves an increase in heart rate and blood pressure, to escape where muscles are prepared to help the animal run away from the threat. Humans produce similar responses to these challenging situations. The nervous system organizes the responses. When animals are faced with a threat nerves send messages to alert the brain, which in turn sends messages to the tissues and organs which need to respond. Nerve cells transfer information using chemicals called neurotransmitters and the researcher will look at how specific neurotransmitters interact at nerve junctions in the brain to produce the right defensive responses. To do this the researcher will use electrophysiological and neuropharmacological approaches. This study is important to help us understand nerve signal processing and could provide us with a mechanism that can be applied to many functions of the brain. This project will also provide training opportunities in physiology for undergraduate and graduate students, and presentations will be made at the elementary school level to encourage interest in science.