Properties of Geometrically Distorted Organic Compounds

这项来自有机动力学项目的拨款支持了耶鲁大学肯尼斯·b·威伯格博士的持续工作。这项研究的结果将为化学反应性依赖于分子结构的方式提供新的见解。维伯格教授将进行的实验将集中在小环碳氢化合物中未活化的碳-碳键的化学和物理性质上。新的和不寻常的小环化合物将被合成，他们的反应性将被检查使用动力学和示踪研究。光谱学方法将用于研究键角变形和取代基效应的影响，理论计算将用于获得基态物种和反应中间体观测性质起源的详细信息。

This grant from the Organic Dynamics Program supports the continuing work of Dr. Kenneth B. Wiberg at Yale University. The results of this investigation will provide new insights into the ways that chemical reactivity is dependent on molecular structure. The experiments that will be carried out by Professor Wiberg will focus on the chemical and physical properties of unactivated carbon-carbon bonds in small-ring hydrocarbons. New and unusual small-ring compounds will be synthesized, and their reactivities will be examined using kinetic and tracer studies. Spectroscopic methods will be used to study the influence of bond angle deformations and substituent effects, and theoretical calculations will be employed to obtain detailed information on the origins of the observed properties for ground-state species and reactive intermediates.