Exploratory Research and Development for use of the Server- Client Paradigm in Geographically Distributed Biological Databases

由Larry Smarr博士领导的伊利诺伊大学国家超级计算应用中心和由Thomas Marr博士领导的冷泉港实验室计算分子生物学小组之间将建立合作关系。此次合作将展示如何将先进的计算技术和软件工具应用于解决分子生物学中的各种问题。立即注意将直接建立一个程序界面和用户界面进入地理分布的生物数据库。程序和用户界面将为驻留在地理上分开的计算机上的数据的查询、检索和分析提供一个统一的环境。具体来说，该项目将包括建立一个基于macintosh的前端系统，以允许相对不熟悉计算机的科学家交互式访问新的关系型基因库的全部信息内容，该系统运行在远程服务器上，可通过T-1互联网连接访问。此外，还将研究使用面向对象数据库技术管理基因组数据的可行性。

A collaboration will be established between the National Center for Supercomputing Applications at the University of Illinois, under the direction of Dr. Larry Smarr, and Computational Molecular Biology Group at Cold Spring Harbor Laboratory, under the direction of Dr. Thomas Marr. This collaboration will demonstrate how advanced computing technology and software tools can be applied to solve a variety of problems in molecular biology. Immediate attention will be directed to building a program interface and a user interface into geographically distributed biological databases. The program and user interfaces will provide a unified environment for query, retrieval, and analysis of data residing on geographically separated computers. Specifically, the project will involve building a Macintosh-based front end system to permit relatively computer-naive scientists interactive access into the full information content of the new, relational version of GenBank, running on a remotely located server accessible over a T-1 internet connection. In addition, investigations will be made into the feasibility of using object- oriented database technology for managing genomic data.