U.S.-Australia Cooperative Workshop: Ions and Water in Biological and Synthetic Membranes; 10-16 August, 1991; Honolulu, Hawaii

该奖项将用于资助将于1991年8月10日至16日在夏威夷檀香山举行的“美国-澳大利亚合作研讨会：生物和合成膜中的离子和水”，由加州大学戴维斯分校的戴维·迪默博士和澳大利亚联邦科学与工业研究组织（CSIRO）的布鲁斯·康奈尔博士组织。细胞膜在细胞过程中发挥着核心作用，参与能量转导反应、离子和营养物质运输以及细胞内环境的稳态调节。为了更好地理解这些过程，有必要在分子水平上回答有关膜功能和结构的某些基本问题。美国和澳大利亚在膜生物物理学领域都有很强的科学实力。然而，这种专门知识在很大程度上是在孤立的情况下发展起来的，这些国家在这一领域的科学家之间只是偶尔进行互动。因此，本次研讨会除了促进科学信息的交流外，其主要目标是发展新的美澳合作，以促进对膜结构和功能的理解。会议主题包括：膜蛋白和多肽的分子结构；膜脂和脂肽相互作用；以及离子电导的生物能学。对这些研究主题的探索在一些情况下产生了潜在的应用，特别是在制药、生物技术、诊断和微电子工业。研讨会的重点是在分子水平上进一步提高对膜功能和结构的基本理解，同时也将包括正在开发与膜生物物理学基础研究相关的商业应用的专家。

This award will support a "U.S.-Australian Cooperative Workshop: Ions and Water in Biological and Synthetic Membranes" to be held 10-16 August 1991 in Honolulu, Hawaii, and to be organized by Dr. David Deamer of the University of California- Davis and Dr. Bruce Cornell of the Australian Commonwealth Scientific and Industrial Research Organization (CSIRO). Membranes play central roles in cellular processes, parti- cipating in energy transduction reactions, ion and nutrient transport, and homeostatic regulation of the intracellular environment. In order to better understand such processes, it is essential to answer certain fundamental questions about membrane function and structure at the molecular level. Both U.S. and Australia have significant scientific strength in the area of membrane biophysics. However, this expertise has grown up largely in isolation with only occasional interaction between the scientists of these countries in this field. For this reason, this workshop, in addition to promoting exchange of scientific information, has as a primary goal the development of new U.S.-Australian collab- orations to advance understanding of membrane structure and function. Themes of the conference include: molecular structure of membrane proteins and peptides; membrane lipidsand lipid-peptide interactions; and the bioenergetics of ion conductance. Exploration of these research themes has in several cases generated potential applications, particularly in pharmaceutical, biotechnological, diagnostic, and microelectronic industries. While the workshop will focus on furthering improved basic understanding of membrane function and structure at the molecular level, participation will also include experts who are developing commercial applications related to basic research in membrane biophysics.