U.S.-Japan Joint Seminar: Biophysical Chemistry of Retinal Proteins/January 1992/Honolulu HI

该奖项为8名美国人的参与提供支持 科学家们在美日联合举办的“生物物理学”研讨会上说， 视网膜蛋白质化学 视网膜的化学 蛋白质是生物物理学的一个迅速兴起的领域。 视网膜- 含有色素的细胞膜是一类 蛋白质介导能量和信息传递。 这一领域的许多研究集中在分子水平上。 转导过程的机制及研究进展 定点突变，序列和结构 中间体的测定和光谱研究 结构和动力学现在呈现出真实的可能性， 确定这些过程的分子机制。 最 对这一领域作出主要贡献的有： 美国和日本的科学家，他们中的许多人， 应该参加这次研讨会。 为此， 研讨会应提供一个极好论坛， 更完整的图片或视网膜转导。 研讨会将于1992年1月12日至18日在 夏威夷大学，檀香山。 协办单位为 Richard Mathies教授，大学化学系 加州伯克利分校的教授和副教授俊明 日本名古屋大学物理系。 研讨会将讨论的具体议题包括（1） 视网膜蛋白质结构与遗传学;（2）发色团 结构和环境;（3）光活化 （4）结构分析和信号转导 （5）色素再生和信号转导。 是的。 这些主题代表了 生物化学、光谱化学和基因工程， 为这个领域做出真实的贡献。 研讨会 将允许来自几个研究小组的代表， 两国会晤并交换信息， 可以带来更广泛的研究合作。

This award provides support for the participation of eight US scientists in a joint US-Japan seminar on "the Biophysical Chemistry of Retinal Proteins". The chemistry of retinal proteins is a rapidly emerging area of biophysics. Retinal- containing pigments are a class of intrinsic membrane proteins the mediate energy and information transduction. Much research in this area concentrates upon the molecular mechanisms of the transduction processes and recent progress on site-specific mutagenesis, sequence and structure determination and spectroscopic studies of intermediate structure and dynamics now present the real possibility of determining the molecular mechanism of these processes. Most of the main contributions to this area have been made by American and Japanese scientists, many of whom it is intended should participate in this seminar. For this reason the seminar should provide an excellent forum for formulating a more complete picture or retinal transduction. The seminar is to be held on January 12-18, 1992 at the University of Hawaii, Honolulu. The co-organizers are Professor Richard Mathies, Department of Chemistry, University of California, Berkeley and Associate Professor Toshiaki Kakitani, Department of Physics, Nagoya University, Japan. Specific topics to be discussed at the seminar include (1) retinal protein structure and genetics; (2) chromophore structure and the environment; (3) photoactivation of retinal-proteins; (4) analysis of structure and transduction mechanisms; and (5) pigment regeneration and signal transduc- tion. These topics represent the right combination of biochemistry, spectrochemistry and genetic engineering to make a real contribution to this subject area. The seminar will permit representatives from several research groups in the two countries to meet and exchange information which could lead to more extensive research collaboration.