U.S.-Japan Joint Seminar: Molecular Biology of Marine Invertebrate Development/April,1991/Honolulu, Hawaii

该奖项支持8名美国科学家参加美日联合举办的“海洋无脊椎动物发育的分子生物学”研讨会。在过去的15年里，主要是通过分子生物学领域的进展，我们在对发展中涉及的主要问题的基本理解方面取得了相当大的进展。海洋无脊椎动物胚胎的研究在这一进程中发挥了重要作用，为分析发育的基本问题提供了很好的模型。例如，通常情况下，精子与卵子的相互作用，特别是受精，一直是海洋无脊椎动物研究的领头羊。另一个非常重要的领域是基因如何控制复杂的形态发生过程，而海洋胚胎的可获得性使它们成为研究这一过程的特别有利的材料。自本世纪初以来，海洋无脊椎动物的发育生物学一直是美国和日本的一个传统上活跃的研究领域，因此这次研讨会应该为两国的研究人员提供一个很好的论坛来比较结果和讨论这一领域的未来研究。研讨会将于1991年4月3日至6日在夏威夷大学火奴鲁鲁大学凯瓦洛海洋实验室举行。联合组织者是加州大学伯克利分校分子细胞生物学系的弗雷德·H·威尔特教授和日本广岛大学动物学系的岛田平久教授。研讨会将集中讨论细胞与细胞的相互作用，包括(1)细胞与环境相互作用的生物学；(2)形态发生的分子生物学；以及(3)特定的基因表达。这次研讨会特别及时，因为这两个国家之间的上一次研讨会是在十年前举行的，自那时以来取得了巨大的进展。预计这次研讨会将带来正在进行的合作项目和科学家之间的交流。

This award provides support for the participation of eight US scientists in a joint US-Japan seminar on "Molecular Biology of Marine Invertebrate Development". In the last 15 years, primarily through advances in the field of molecular biology, considerable progress has been made in our basic understanding of the major issues involved in development. The study of marine invertebrate embryos has played an important role in this progress by providing a good model for analyzing the fundamental problems of development. For example, sperm-egg interactions in general and fertilization in particular have always been areas where marine invertebrate research has lead the way. Another area of immense importance is how genes preside over the complex process of morphogenesis, and the accessibility of marine embryos makes them a particularly favorable material for the study of this process. Development- al biology of marine invertebrates has been a traditionally active field of research in both the US and Japan since the beginning of this century and this seminar should therefore provide an excellent forum for researchers in the two countries to compare results and discuss future research in this area. The seminar is to be held on April 3-6 1991 at the Kewalo Marine Laboratory of the University of Hawaii, Honolulu, Hawaii. The co-organizers are Professor Fred H Wilt, Molecular cell biology unit, University of California, Berkeley, and Professor Hiraku Shimada, Department of Zoology, Hiroshima University, Japan. Specific topics to be discussed at the seminar will concentrate on cell-cell interactions including (1) the biology of cell-environmental interactions; (2) the molecular biology of morphogenesis; and (3) specific gene expression. The seminar is especially timely as the last seminar in this topic, between these two countries, was held ten years ago and enormous advances have been achieved since that time. It is expected that ongoing collaborative projects and exchanges of scientists will occur as a result of this seminar.