Brain-skull interface: discovering the missing piece of head biomechanics

脑-颅骨界面：发现头部生物力学缺失的部分

• 批准号: DP230100949
• 负责人: Prof Adam Wittek
• 金额: $ 39.97万
• 依托单位: The University of Western Australia
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2023
• 资助国家: 澳大利亚
• 起止时间: 2023-01-01 至 2025-12-31
• 项目状态: 未结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP230100949
• 关键词: Brain; skull; interface; discovering; missing

Overall objective of this project is to measure, mathematically describe and implement in software mechanical properties of brain-skull interface – a critical component of current large and sophisticated computational models of the brain and the last missing piece of brain biomechanics knowledge. This will allow increased reliability of comprehensive biomechanical models used to simulate realistic injury and surgery scenarios. The problem is significant and urgent. Every year in Australia, there are over 22,000 cases of traumatic brain injury, some of which could be prevented by better passive and active countermeasures; and over 12,000 neurosurgical procedures that surgical simulation could make more accurate and therefore safer.

该项目的总体目标是测量，数学描述和实现在软件中的脑-颅骨界面的机械性能-一个关键组成部分，目前大型和复杂的计算模型的大脑和最后一块缺失的大脑生物力学知识。这将提高用于模拟真实损伤和手术场景的综合生物力学模型的可靠性。 这是一个重大而紧迫的问题。在澳大利亚，每年有超过22，000例创伤性脑损伤病例，其中一些可以通过更好的被动和主动对策来预防;手术模拟可以使超过12，000例神经外科手术更准确，因此更安全。