Presidential Young Investigator Award/Metal-Ligand Multiple Bonds and Atom Transfer Processes

爱荷华州立大学的L. Keith Woo博士是无机、生物无机和有机金属化学项目的总统青年研究员。吴博士的研究项目涉及过渡金属化合物（如铁和钼）的不寻常反应，其中两个甚至三个电子同时转移。人们对这些过程知之甚少，并提出了新的实验和理论挑战。已知的这种反应的例子包括卟啉的金属配合物，它与血红蛋白中的铁结合中心有关。研究了金属卟啉之间的多电子氧化还原反应以及相应的氮原子或氧原子转移。该项目的具体目标包括描述氮原子和氧原子转移的范围和普遍性，确定这些过程的热力学和动力学参数如何随着分子（结构、电子）变化而变化，并阐明了这些过程与其他多电子过程如固氮和氧活化的关系。

Dr. L. Keith Woo of the Iowa State University is supported as a Presidential Young Investigator by the Inorganic, Bioinorganic and Organometallic Chemistry Program. Dr. Woo's project is concerned with unusual reactions of compounds of transition metals, such as iron and molybdenum, in which two or even three electrons are transferred simultaneously. Such processes are poorly understood and present new experimental and theoretical challenges. The known examples of such reactions involve metal complexes of porphyrins, which are related to the iron-binding center in hemoglobin. Multi-electron redox reactions, and the accompanying nitrogen or oxygen atom transfers, between metalloporphyrins will be investigated. The specific goals of the project include delineating the scope and generality of nitrogen and oxygen atom transfer, determining how thermodynamic and kinetic parameters of these processes vary as a function of molecular (structural, electronic) changes, and elucidating the relationship of these processes to other multi-electron processes such as nitrogen fixation and oxygen activation.