Mechanisms of cell clearance during tissue homeostasis and regeneration using freshwater planarians

淡水涡虫组织稳态和再生过程中的细胞清除机制

• 批准号: 379429
• 负责人: Pearson Bret
• 金额: $ 48.76万
• 依托单位: Hospital for Sick Children (Toronto)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-03-01 至 2023-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=379429&lang=en
• 关键词: Cell Clearance; Cell Engulfment; Lineage Development; Neural Regeneration; Phagocytosis; Planarians; Single-Cell Rna-Sequencing; Spinal Cord Injury; Tumor Suppression; Zebrafish

Humans replace billions of cells every day, a process of which requires making the correct number and type of new cells, and removing old cells. In order to dissect this biology in the lab, and model system is required that has high levels of cell turnove

人类每天更换数十亿个细胞，这一过程需要制造正确数量和类型的新细胞，并去除旧细胞。为了在实验室中剖析这种生物学，需要具有高水平细胞翻转的模型系统