Novel Unsaturated Species and Intermediates and Their Chemistry

在有机动力学项目的支持下，斯坦博士将继续研究新的不饱和物种和中间体及其化学。斯坦博士将从事的具体研究领域包括：(i)双原子碳和由双原子碳衍生的酰基化合物的生成和化学，（ii） Ni-Pd-Pt介导的不饱和交叉偶联和不饱和羧化的机理，（iii）均相碳氢键活化和杂双金属配合物，（iv）高应变环体系的合成和化学，(5)合成（可能是稳定的）氙-碳物质。Stang博士的项目涉及机械（物理有机）和有机金属化学的几个领域，其长期目标包括：(1)新型反应中间体（例如，双原子碳，不饱和碳）的合成，表征和化学各方面的研究，以及(2)有机金属反应的基本机理研究，如乙烯基交叉偶联和碳氢键的均匀活化。预计这一广泛而多样的基础研究项目将提供(i)对广泛使用的现代合成反应的新的机理见解和（ii）在溶液中合成活性中间体的新途径。

With support from the Organic Dynamics Program, Dr. Stang will continue to study novel unsaturated species and intermediates and their chemistry. Specific areas of research to be pursued by Dr. Stang include: (i) generation and chemistry of diatomic carbon and ylides derived from diatomic carbon, (ii) mechanism of Ni-Pd-Pt mediated unsaturated cross-couplings and unsaturated carboxylations, (iii) homogeneous C-H bond activation and heterobimetallic complexes, (iv) synthesis and chemistry of highly strained ring systems, and (v) synthesis of (presumably stable) xenon-carbon species. The long-range objectives of Dr. Stang's project, which is concerned with several areas of mechanistic (physical-organic) and organometallic chemistry, include: (i) synthesis, characterization, and studies of various aspects of the chemistry of novel reactive intermediates (e.g., diatomic carbon, unsaturated carbenes), and (ii) fundamental mechanistic studies of such organometallic reactions as vinylic cross-coupling and homogeneous activation of carbon-hydrogen bonds. It is anticipated that this broad and diverse program of fundamental research will provide (i) new mechanistic insight into extensively used modern synthetic reactions and (ii) new routes for synthesizing reactive intermediates in solution.