Long and Medium-Term Research: Synthesis and Characteri- zation of Conducting Polymers Composed of Porphyrins Linked by Molecular Recognition Molecules

中长期研究：由分子识别分子连接的卟啉组成的导电聚合物的合成和表征本奖项由国外卓越中心长期和中期研究计划资助。使美国研究人员能够在国外卓越的研究中心工作3至12个月，并提供联合研究的机会，以及使用独特或互补的设施，国外专业知识和实验条件。该奖项将支持洛克菲勒大学的Charles M. Drain博士和法国斯特拉斯堡路易斯巴斯德研究所的Jean-Marie Lehn教授进行为期12个月的访问。在自然界中发现了各种分子自发自组装系统：疏水性和亲水性相互作用使脂质进入液晶膜；氢键和静电相互作用引起DNA碱基对的分子识别，产生特定的螺旋结构；离子力将固态晶格排列成晶体。所有这些都依赖于互补成分之间的分子识别。由于通过给定介质的有效电子传导要求它高度组织成特定的晶体或分子晶格，这种结构很难在有机聚合物和薄膜中实现，Drain博士建议使用自组装系统来制造导电聚合物和合成卟啉薄膜。他将使用互补的分子识别部分，这是Lehn教授已经描述过的氢键分子的衍生物。Drain博士将合成并表征三组卟啉，这些卟啉由分子识别分子衍生而成，产生单、二和四取代的中-四烷基卟啉。单取代和二取代的卟啉通过两种不同的插层几何形状形成介晶相和结晶相，而四取代的卟啉则在固体载体上形成高度有序的单层。Drain博士建议合成、表征和检查这些阵列的物理性质，包括测量脂质双分子层和固体载体（如氧化锡）上的聚合物电导和光电压。奖学金建议提供国际旅行费用和美国本土机构250美元的固定行政津贴。

Long & Medium-Term Research: Synthesis and Characterization of Conducting Polymers Composed of Porphyrins Linked by Molecular Recognition Molecules This award is made under the Program for Long- & Medium- Term Research at Foreign Centers of Excellence, which enables U.S. researchers to work 3 to 12 months abroad at research centers of proven excellence, and to provide opportunities for joint research, and the use of unique or complementary facilities, expertise and experimental conditions abroad. This award will support a 12-month visit by Dr. Charles M. Drain of The Rockefeller University with Professor Jean-Marie Lehn of Institut Louis Pasteur, Strasbourg, France. Various molecular, spontaneously self assembling systems are found in nature: hydrophobic and hydrophilic interactions put lipids into liquid crystalline membranes; hydrogen bonding and electrostatic interactions cause molecular recognition of DNA base pairs creating specific helical structures; and ionic forces arrange solid state lattices into crystals. All rely on molecular recognition between complementary components. As effective electronic conduction through a given media requires it be highly organized into a specific crystalline or molecular lattice, structures difficult to achieve in organic polymers and films, Dr. Drain proposes to use self assembling systems to create conducting polymers and films of synthetic porphyrins. He will use complementary molecular recognition moieties which are derivatives of hydrogen bonding molecules already described by Professor Lehn. Dr. Drain will synthesize and characterize three sets of porphyrins derivatized with the molecular recognition molecules resulting in mono, di, and tetra substituted meso-tetra-alkylporphyrins. The mono- substituted and the di-substituted porphyrins should form mesomorphic and crystalline phases via two different porphyrin intercalation geometries, while the tetra- substituted porphyrin should form highly organized monolayers on solid supports. Dr. Drain proposes to synthesize, characterize, and examine the physical properties of these arrays, including measurement of polymeric conductance and photovoltage both in lipid bilayers and on solid supports such as tin oxide. The award recommendation provides funds to cover international travel and a flat administrative allowance of $250 for the U.S. home institution.