CCD-based Laboratory Detector System for x-ray Crystallography

该开发项目将提供一个基于ccd的x射线区域探测器系统，用于收集和处理使用实验室x射线源的蛋白质晶体和其他大分子组件的衍射数据。该探测器将有一个115毫米直径的有源区域，1024 × 1024分辨率的元素，动态范围为4000，DQE高达0.6，读出时间为6秒。该系统将是一个经过全面测试的集成数据收集包，包括探测器、基于unix的工作站、软件、测角仪和文档。在设计时将考虑各部件的性能、成本、可用性和可靠性，使系统能够广泛分布。单个组件将被彻底表征，并通过收集各种蛋白质晶体的数据对整个系统进行广泛测试。这个集成系统将准备好使用，不需要进一步的硬件或软件开发。

This development project will provide a CCD-based x-ray area detector system for collecting and processing diffraction data form protein crystals and other macromolecular assemblies using laboratory x-ray sources. The detector will have a 115 mm- diameter active area, 1024X 1024 resolution elements, a dynamic range of 4000, a DQE of up to 0.6, and a readout time of 6 seconds. The system will be a fully-tested, integrated data- collection package, and include the detector, a UNIX-based workstation, software, a goniometer, and documentation. The performance, cost, availability and reliability of each component will be considered n the design, so that the system can be widely distributed. The individual components will be thoroughly characterized, and the complete system tested extensively by collecting data from a variety of protein crystals. This integrated system will be ready for use, without need for further hardware or software development.