Fundamentals and Analytical Applications of Hypervalent Radical Chemistry

超价自由基化学的基础和分析应用

• 批准号: 9102442
• 负责人: Frantisek Turecek
• 金额: $ 16.35万
• 依托单位: University of Washington
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-04-15 至 1994-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9102442&HistoricalAwards=false
• 关键词: Fundamentals; Analytical; Applications; Hypervalent; Radical

With support from the Organic Dynamics Program, Dr. Turecek will investigate the preparations, stabilities, and dissociations of hypervalent oxonium, ammonium, and sulfonium radicals that are generated and analyzed via neutralization- reionization mass spectrometry. In addition, fragmentations of neutral species will be employed for the structural elucidation of complex organic compounds by mass spectrometry. %%% Hypervalent radicals represent a class of unstable species in which the formal valence of an atom exceeds its normal coordination number in the given oxidation state. Dissociations of small hypervalent radicals often display deuterium (H-2) and O-18 isotope effects of unusual magnitude; the nature of these effects is not well understood. Dr. Turecek will study hypervalent radicals in the gas phase by employing the recently developed technique of neutralization reionization mass spectrometry. In the gas phase, hypervalent radicals can undergo exothermic dissociations to afford stable products. Thus, these species hold promise as a novel method by which mass spectroscopy can be used for organic structural analysis.

在有机动力学项目的支持下， 将调查的准备工作，稳定性， 高价氧鎓、铵和锍的离解 通过中和产生和分析的自由基- 再电离质谱此外， 将采用中性物质进行结构解析 复杂有机化合物的质谱分析 %%% 超价自由基代表了一类不稳定的物种， 原子的形式价态超过其正常价态 在给定的氧化态下的配位数。解离 小的超价自由基通常显示氘（H-2）， O-18同位素效应的不寻常的幅度;这些性质 效果还不太清楚。图雷切克医生将研究 超价自由基在气相中，通过采用最近的 中和再电离质量改进技术 光谱法在气相中，超价自由基可以 进行放热解离以提供稳定的产物。 因此，这些物种有望成为一种新的方法， 质谱可用于有机结构分析。