Fundamentals and Analytical Applications of Hypervalent Radical Chemistry

在有机动力学项目的支持下，Turecek博士将研究通过中和-再电离质谱法生成和分析的高价氧、铵和磺胺自由基的制备、稳定性和解离。此外，中性物质的碎片将被用于复杂有机化合物的质谱结构解析。高价自由基代表一类不稳定的物质，其中原子在给定氧化态下的形式价超过其正常配位数。小的高价自由基的解离通常显示出异常大小的氘（H-2）和O-18同位素效应；这些影响的性质尚不清楚。Turecek博士将采用最新开发的中和再电离质谱技术研究气相中的高价自由基。在气相中，高价自由基可以进行放热解离以产生稳定的产物。因此，这些物种有望成为一种新的方法，通过质谱法可以用于有机结构分析。

With support from the Organic Dynamics Program, Dr. Turecek will investigate the preparations, stabilities, and dissociations of hypervalent oxonium, ammonium, and sulfonium radicals that are generated and analyzed via neutralization- reionization mass spectrometry. In addition, fragmentations of neutral species will be employed for the structural elucidation of complex organic compounds by mass spectrometry. %%% Hypervalent radicals represent a class of unstable species in which the formal valence of an atom exceeds its normal coordination number in the given oxidation state. Dissociations of small hypervalent radicals often display deuterium (H-2) and O-18 isotope effects of unusual magnitude; the nature of these effects is not well understood. Dr. Turecek will study hypervalent radicals in the gas phase by employing the recently developed technique of neutralization reionization mass spectrometry. In the gas phase, hypervalent radicals can undergo exothermic dissociations to afford stable products. Thus, these species hold promise as a novel method by which mass spectroscopy can be used for organic structural analysis.