Microstructural Modeling of the Bone Implant Interface

骨植入物界面的微观结构建模

• 批准号: 9103236
• 负责人: Stephen Cowin
• 金额: $ 16.16万
• 依托单位: CUNY City College
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-08-01 至 1994-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9103236&HistoricalAwards=false
• 关键词: Microstructural; Modeling; Bone; Implant; Interface

This proposal is an extension of the PI's previous theoretical work on the response of bone to mechanical stresses. The intent is to extend the mathematical theory to describe the changes that occur at the bone-implant interface. A computational procedure known as boundary element method will be used to analyze the microstructural remodeling of bone and to determine the variation in mechanical stability as a function of time. If the theory is proven correct, the work will lead to the improved design of bone protheses.

该提案是 PI 之前关于骨骼对机械应力响应的理论工作的延伸。 目的是扩展数学理论来描述骨-植入物界面处发生的变化。 称为边界元法的计算程序将用于分析骨骼的微观结构重塑并确定机械稳定性随时间的变化。 如果该理论被证明是正确的，这项工作将导致骨假体设计的改进。