The Developmental Regulation of Cellulose Synthesis in Dictyostelium discoideum

纤维素合成是植物的重要活性， 细胞黏菌Dictyosteelium的分化细胞 盘状突，但纤维素在发育过程中的作用和 控制其合成受到很少的关注， 文学该项目的目标是： 纤维素合成的速率、位点和时间;分析 在四种不同的细胞外结构中发现的纤维素 看看纤维素中是否存在生物物理差异， 可能与细胞结构或控制的差异有关; 以确定纤维素合成是否在任何时候都是细胞类型 具体过程;描述纤维素之间的相互作用 和细胞外基质蛋白在构建茎管中的作用; 来鉴定那些不能合成 纤维素或以某种方式改变其纤维素合成; 并鉴定纤维素合成酶基因，从而研究 纤维素合成的分子控制。的结果 项目的重要性不仅在于它们将作出的贡献， 我们对D的认识盘状突发育，而且 他们可能告诉我们关于控制纤维素合成的信息， 植物

Cellulose synthesis is a significant activity of the differentiating cells of the cellular slime mold Dictyostelium discoideum, but the role of cellulose during development and the control of its synthesis have received little attention in the literature. The objectives of this project are: to determine the rates, sites, and timing of cellulose synthesis; to analyze the cellulose found in each of four distinct extracellular structures to see if there are biophysical differences in the cellulose that can be related to differences in cellular structures or control; to determine if cellulose synthesis is at any time a cell-type specific process; to describe the interactions between cellulose and extracellular matrix proteins in structuring the stalk tube; to characterize mutant strains that are unable to synthesize cellulose or are somehow altered in their cellulose synthesis; and to identify the gene for cellulose synthase and thereby study the molecular control of cellulose synthesis. The results of this project are significant not only for the contribution they will make to our knowledge of D. discoideum development, but also for what they may tell us about the control of cellulose synthesis in plants.