Cellular and Molecular Events in Early Leech Development
Cellular and Molecular Events in Early Leech Development
批准号:
9105713
负责人:
David Weisblat
金额:
$32.37万
依托单位国家:
美国
项目类别:
Continuing Grant
财政年份:
1991
资助国家:
美国
项目状态:
已结题
起止时间:
1991-11-01 至 1994-10-31
中文摘要
点击翻译按钮获取中文摘要
英文摘要
Glossiphoniid leech embryos, such as those of the species Helobdella triserialis, are well suited for studying cellular aspects of early development, because they are relatively large and hardy, and because their blastomeres are both experimentally accessible and individually identifiable. Thus, experimental analyses can be carried out on developmentally equivalent cells from one embryo to the next. This proposal is to continue previous analyses of various aspects of leech development, including: the role of cytoplasmic determinants in determining early cleavage; the specification of mesodermal and ectodermal cell lines; fate determining interactions between initially equipotent cells; the continuing refinement of developmental cell lineages; the influence of a transient embryonic epithelium on morphogenesis. The experiments proposed will carry out these analyses at the cellular and molecular level, by incorporating the techniques of the "reverse genetic approach" in combination with those used previously, such as microinjection of cell lineage tracers and other materials into identified embryonic cells, single cell ablation and optical microscopy.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Unequal Cleavage and D Quadrant Specification in the Leech Helobdella
-
批准号:0922792
-
项目类别:Standard Grant
-
资助金额:$35.0万
-
财政年份:2009
-
负责人:David Weisblat
-
依托单位:
An NSF REU Site at Berkeley: Cell, Developmental and Evolutionary Biology
-
批准号:0852016
-
项目类别:Continuing Grant
-
资助金额:$45.05万
-
财政年份:2009
-
负责人:David Weisblat
-
依托单位:
REU Site in Cell, Developmental and Evolutionary Biology at UC Berkeley
-
批准号:0552996
-
项目类别:Continuing Grant
-
资助金额:$0.0万
-
财政年份:2006
-
负责人:David Weisblat
-
依托单位:
Cellular and Molecular Events in Early Leech Development
-
批准号:0314718
-
项目类别:Continuing Grant
-
资助金额:$40.0万
-
财政年份:2004
-
负责人:David Weisblat
-
依托单位:
Cellular and Molecular Events in Early Leech Development
-
批准号:0091261
-
项目类别:Continuing Grant
-
资助金额:$36.0万
-
财政年份:2001
-
负责人:David Weisblat
-
依托单位:
Cellular and Molecular Events in Early Leech Development
-
批准号:9723114
-
项目类别:Continuing Grant
-
资助金额:$31.0万
-
财政年份:1997
-
负责人:David Weisblat
-
依托单位:
Cellular and Molecular Events in Early Leech Development
-
批准号:9406141
-
项目类别:Continuing Grant
-
资助金额:$28.5万
-
财政年份:1994
-
负责人:David Weisblat
-
依托单位:
Summer Course in Cellular Neurobiology and Development of the Leech; August 5-25, 1991; Woods Hole, Massachusetts
-
批准号:9109261
-
项目类别:Standard Grant
-
资助金额:$4.26万
-
财政年份:1991
-
负责人:David Weisblat
-
依托单位:
1989 West Coast Regional Developmental Biology Conference, Standford Alumni Center, Fallen Leaf Lake, California, May 4-7, 1989
-
批准号:8819124
-
项目类别:Standard Grant
-
资助金额:$0.2万
-
财政年份:1989
-
负责人:David Weisblat
-
依托单位:
Early Events in Leech Embryogenesis
-
批准号:8711262
-
项目类别:Continuing Grant
-
资助金额:$27.11万
-
财政年份:1987
-
负责人:David Weisblat
-
依托单位:
Cell Lineage and Cell Interaction in Leech Development
-
批准号:8409785
-
项目类别:Continuing Grant
-
资助金额:$32.48万
-
财政年份:1984
-
负责人:David Weisblat
-
依托单位:
国内基金
海外基金
登录
查看更多内容
Kidney injury molecular(KIM-1)介导肾小管上皮细胞自噬在糖尿病肾病肾间质纤维化中的作用
-
批准号:81300605
-
项目类别:青年科学基金项目
-
资助金额:23.0万元
-
批准年份:2013
-
负责人:唐琳
-
依托单位:
Molecular Plant
-
批准号:31224801
-
项目类别:专项基金项目
-
资助金额:20.0万元
-
批准年份:2012
-
负责人:黄健秋
-
依托单位:
Molecular Interaction Reconstruction of Rheumatoid Arthritis Therapies Using Clinical Data
-
批准号:31070748
-
项目类别:面上项目
-
资助金额:34.0万元
-
批准年份:2010
-
负责人:Christine Nardini
-
依托单位:
Molecular Plant
-
批准号:31024802
-
项目类别:专项基金项目
-
资助金额:20.0万元
-
批准年份:2010
-
负责人:陈晓亚
-
依托单位:
Cellular & Molecular Immunology
-
批准号:30824806
-
项目类别:专项基金项目
-
资助金额:20.0万元
-
批准年份:2008
-
负责人:魏海明
-
依托单位: