Molecular Biology of Arabiodopsis

拟南芥分子生物学

• 批准号: 9107793
• 负责人: Gerald Fink
• 金额: $ 30万
• 依托单位: Whitehead Institute for Biomedical Research
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-08-01 至 1994-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9107793&HistoricalAwards=false
• 关键词: Molecular; Biology; Arabiodopsis

Arabidopsis thaliana is a plant that is emerging as a model for understanding plant genetics, development and physiology at the molecular level. It has many characteristics that make it more amenable to molecular inquiry than are other flowering plants and yet because it is a flowering plant, has many homologous DNA sequences and genes which can be used to both isolate and understand gene action in plants with less accessible genomes. The laboratory headed by Dr. Gerald Fink has been in the forefront of those using Arabidopsis to ask questions which have been unanswerable in previous work with plants. The biosynthetic pathway for aromatic amino acids is under study and that study has already provided information suggesting that differences exist between the pathway in animals and plants. Continuation of this work requires more appropriate facilities for growing plants under controlled conditions. The greenhouse, which will be built on the roof of the Whitehead Biomedical Institute, will allow the continuation and expansion of research using plants as experimental organisms by scientists in Dr. Fink's laboratory as well as others at the Institute.***//

拟南芥是一种正在成为在分子水平上理解植物遗传学、发育和生理学的模型的植物。 它具有许多特征，使其比其他开花植物更适合分子研究，但由于它是开花植物，因此具有许多同源 DNA 序列和基因，可用于分离和理解基因组不易获取的植物中的基因作用。 杰拉尔德·芬克博士领导的实验室一直走在利用拟南芥提出以前植物研究中无法回答的问题的前沿。 芳香族氨基酸的生物合成途径正在研究中，该研究已经提供的信息表明动物和植物中的途径之间存在差异。 这项工作的继续需要更合适的设施来在受控条件下种植植物。 该温室将建在怀特海德生物医学研究所的屋顶上，将允许芬克博士实验室的科学家以及该研究所的其他人员继续和扩大使用植物作为实验生物的研究。***//