Regulation of Ovulation in the Domestic Hen

排卵是动物界的普遍现象。 然而，人们对这个过程知之甚少。 据知， 促黄体生成激素（LH），由脑垂体产生 引起毛囊壁的一些变化， 卵细胞壁破裂并释放出卵子。 的 滤泡壁由必须降解的厚基质组成 以允许排卵。 为了促进排卵，卵泡壁 有一个专门的区域叫做柱头， 以平行的方式排列。 根据对其他物种的研究， 假设酶如组织纤溶酶原 激活剂和胶原酶，或者解离或者降解纤维 在柱头区域。 本研究的目的是测量 这两种关键酶在卵泡中的活性， 促进排卵 从这些研究中获得的知识将 促进对LH产生的机制的理解 时间控制卵泡壁的变化， 发生在可预测的时间。 //

Ovulation is a universal phenomenon in the animal kingdom. However, this process is poorly understood. It is known that a hormone, luteinizing hormone (LH), produced by the pituitary induces a number of changes in the follicular wall which results in a rupture of this wall and release of the egg or ovum. The follicular wall consists of a thick matrix which must be degraded to permit ovulation. To facilitate ovulation, the follicular wall has a specialized region called a stigma in which the fibers are arranged in a parallel manner. Based on studies in others species, it is hypothesized that enzymes, such as tissue plasminogen activator and collagenase, either dissociate or degrade the fibers in the stigma region. The purpose of this study is to measure the activities of these two key enzymes in the follicle as it ap- proaches ovulation. Knowledge obtained from these studies will promote an understanding of the mechanisms by which LH brings about time controlled changes in the follicular wall so that ovulation occurs at a predictable time. //