Regulation of Ovulation in the Domestic Hen

众所周知，一种由脑下垂体产生的荷尔蒙--黄体生成素会引起卵泡壁的一系列变化，从而导致卵泡壁的破裂和卵子或卵子的释放。这项建议的目的是阐明黄体生成素作用于排卵前卵泡颗粒层和膜层诱导排卵的机制。需要检验的假设是，促黄体生成素在诱导母鸡排卵中的主要作用之一涉及到纤溶酶原激活剂和胶原酶的产生。这些关键酶要么解离柱头区域的纤维，要么降解柱头区域的纤维。这项研究将带来新的基本发现。

It is known that a hormone, luteinizing hormone (LH), produced by the pituitary gland induces a number of changes in the follicular wall which results in a rupture of this wall and release of the egg or ovum. The goal of this proposal is to elucidate the mechanism through which luteinizing hormone acting on the granulosa and theca layers of preovulatory follicule induces ovulation. The hypothesis to be tested is that one of the primary roles of LH in the induction of ovulation in the hen involves production of the plasminogen activator and collagenase. These key enzymes either dissociate or degrade the fibers in the stigma region. This research will lead to new fundamental findings.