Genetic Hyperviariability in Halobacterium Halobium

盐杆菌的遗传高活力

• 批准号: 9108514
• 负责人: Shiladitya DasSarma
• 金额: $ 6.05万
• 依托单位: University of Massachusetts Amherst
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1992
• 资助国家: 美国
• 起止时间: 1992-02-15 至 1993-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9108514&HistoricalAwards=false
• 关键词: Genetic; Hyperviariability; Halobacterium; Halobium

The archaebacterium Halobacterium halobium contains intracellular gas-filled vesicles that confer buoyancy to the cell. Research will be carried out on the development of a cloning vector for this organism, using the plasmid which contains the genes for the gas vesicles. Studies of the loci involved with plasmid stability are being undertaken in order to determine the mechanism responsible for a class of vesicle mutants which are partially vac and extremely unstable.

古细菌盐杆菌含有细胞内充满气体的囊泡，赋予细胞浮力。 将利用含有气体囊泡基因的质粒，研究开发该生物体的克隆载体。 正在对与质粒稳定性有关的基因座进行研究，以确定导致一类部分空且极其不稳定的囊泡突变体的机制。