Effect of the selective MT1 receptor partial agonist UCM871 in the activity of noraphineprine neurons of the locus coeruleus during the sleep/wake cycle

选择性 MT1 受体部分激动剂 UCM871 对睡眠/觉醒周期中蓝斑去甲肾上腺素神经元活性的影响

• 批准号: 400223
• 负责人: Lopez-Canul Martha G
• 金额: $ 0.04万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-01-01 至 2020-01-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=400223&lang=en
• 关键词: Locus Coeruleus; Melatonin; Melatonin Receptors; Rem Sleep; Sleep/Wake Cycle; Ucm871

Melatonin is a neurohormone produced in the pineal gland which is involved in numerous physiological functions, including sleep regulation, via its receptors MT1 and MT2. The Locus Coeruleus (LC) nucleus contain critical wakefulness-promoting neurons whic

褪黑激素是松果体中产生的神经激素，其通过其受体MT1和MT2参与许多生理功能，包括睡眠调节。蓝斑核（LC）含有关键的唤醒促进神经元，