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Defining the immune dysfunction in childhood nephrotic syndrome: Toward therapeutic reversal without glucocorticoids

Defining the immune dysfunction in childhood nephrotic syndrome: Toward therapeutic reversal without glucocorticoids
定义儿童肾病综合征的免疫功能障碍：在不使用糖皮质激素的情况下实现治疗逆转
批准号：
400829
负责人：
Takano Tomoko
金额：
$60.47万
依托单位：
Research Institute of the McGill University Health Centre
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2019
资助国家：
加拿大
项目状态：
已结题
起止时间：
2019-03-01 至 2024-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=400829&lang=en
关键词：
Lymphocytes Minimal Change Disease Nephrotic Syndrome Rituximab

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中文摘要
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英文摘要
Nephrotic syndrome is the most common kidney disease among children. Affected children have massive leakage of protein into the urine and as a consequence, develop body swelling (edema). Most children respond to treatment with steroids, however many of th
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Pathogenesis of idiopathic nephrotic syndrome: defining the role of B cells and autoantibodies reactive to podocyte proteins
Defining the immune dysfunction in childhood nephrotic syndrome: Toward therapeutic reversal without glucocorticoids
Role of beta-PIX and CdGAP in the pathogenesis of proteinuria
Role of RhoGDIalpha in the pathogenesis of congenital and childhood nephrotic syndrome
  • 批准号：
    266879
  • 项目类别：
    Operating Grants
  • 资助金额：
    $49.07万
  • 财政年份：
    2012
  • 负责人：
    Takano Tomoko
  • 依托单位：
    McGill University
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