Pathogenesis of idiopathic nephrotic syndrome: defining the role of B cells and autoantibodies reactive to podocyte proteins

特发性肾病综合征的发病机制：定义 B 细胞和足细胞蛋白反应性自身抗体的作用

• 批准号: 487849
• 负责人: Takano Tomoko
• 金额: $ 69.66万
• 依托单位: Research Institute of the McGill University Health Centre
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2023
• 资助国家: 加拿大
• 起止时间: 2023-09-01 至 2028-09-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=487849&lang=en
• 关键词: Nephrotic Syndrome

Kidneys act as a barrier that filters water and waste products into urine while retaining important proteins in blood. When this barrier is damaged, massive leakage of proteins into urine (proteinuria) occurs, leading to a condition known as nephrotic syn

肾脏作为一个屏障，过滤水和废物进入尿液，同时保留血液中的重要蛋白质。当这个屏障被破坏时，大量蛋白质泄漏到尿液中（蛋白尿），导致称为肾病综合征的疾病。