Defining the immune dysfunction in childhood nephrotic syndrome: Toward therapeutic reversal without glucocorticoids

定义儿童肾病综合征的免疫功能障碍：在不使用糖皮质激素的情况下实现治疗逆转

• 批准号: 394681
• 负责人: Takano Tomoko
• 金额: $ 7.29万
• 依托单位: Research Institute of the McGill University Health Centre
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-09-01 至 2019-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=394681&lang=en
• 关键词: Lymphocytes; Minimal Change Disease; Nephrotic Syndrome; Rituximab

Nephrotic syndrome is the most common kidney disease among children. Affected children have massive leakage of protein into the urine and as a consequence, develop body swelling (edema). Most children respond to treatment with steroids, however many of th

肾病综合征是儿童中最常见的肾脏疾病。受影响的儿童有大量的蛋白质渗入尿液，结果导致身体肿胀(浮肿)。大多数儿童对类固醇治疗有反应，但许多