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Regulation of SLC43A3 expression and function, and its impact on 6-mercaptopurine cytotoxicity and resistance in the treatment of leukemia

Regulation of SLC43A3 expression and function, and its impact on 6-mercaptopurine cytotoxicity and resistance in the treatment of leukemia
SLC43A3表达和功能的调控及其对6-巯基嘌呤治疗白血病细胞毒性和耐药性的影响
批准号:
408712
负责人:
Hammond James R
金额:
$46.81万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2019
资助国家:
加拿大
项目状态:
已结题
起止时间:
2019-09-01 至 2024-09-01

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中文摘要
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英文摘要
6-Mercaptopurine (6-MP) is used in combination with other drugs to treat acute lymphoblastic leukaemia (ALL). It is well known that not all patients respond to this drug to the same degree, with the therapeutic success rate declining with patient age. To
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A Novel, Genetically Modified Mouse Model of Diffuse Idiopathic Skeletal Hyperostosis and Related Hypermineralization Disorders in the Elderly
  • 批准号:
    226761
  • 项目类别:
    Operating Grants
  • 资助金额:
    $41.07万
  • 财政年份:
    2011
  • 负责人:
    Hammond James R
  • 依托单位:
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