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A Novel, Genetically Modified Mouse Model of Diffuse Idiopathic Skeletal Hyperostosis and Related Hypermineralization Disorders in the Elderly

A Novel, Genetically Modified Mouse Model of Diffuse Idiopathic Skeletal Hyperostosis and Related Hypermineralization Disorders in the Elderly
一种新型转基因小鼠模型，用于治疗老年人弥漫性特发性骨骼肥厚和相关的矿化过度疾病
批准号：
226761
负责人：
Hammond James R
金额：
$41.07万
依托单位：
University of Western Ontario
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2011
资助国家：
加拿大
项目状态：
已结题
起止时间：
2011-03-01 至 2016-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=226761&lang=en
关键词：
Adenosine Aging Arthritis Bone Mineralization Nucleoside Transport Purine Metabolism Spine

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中文摘要
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英文摘要
Diffuse Idiopathic Skeletal Hyperostosis (DISH) is a disease of the elderly characterized by mineralization of the spinal ligaments. It is a relatively common condition, with prevalence around 20% in men and slightly less in women over the age of 65. Sym
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Regulation of SLC43A3 expression and function, and its impact on 6-mercaptopurine cytotoxicity and resistance in the treatment of leukemia
  • 批准号：
    408712
  • 项目类别：
    Operating Grants
  • 资助金额：
    $46.81万
  • 财政年份：
    2019
  • 负责人：
    Hammond James R
  • 依托单位：
    University of Alberta
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