COLLABORATIVE PROJECT: Molecular Studies Of Juvenile Hormone Action
合作项目:保幼激素作用的分子研究
基本信息
- 批准号:9119332
- 负责人:
- 金额:$ 21万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Continuing Grant
- 财政年份:1991
- 资助国家:美国
- 起止时间:1991-09-15 至 1994-08-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
The proposed research, jointly supported by the Division of Cellular Biosciences and the Division of Chemistry, is the continuation of an interdisciplinary project to understand the action of juvenile hormone at the molecular level combining the disciplines of chemistry, molecular biology, and physiology. Major keys include understanding the molecular basis for hormonal regulation of gene expression in insects (L.M. Riddiford), biochemical and molecular studies of JH metabolism and synthesis (B.D. Hammock), and use of high specific activity labeled JHs and JHs (G.D. Prestwich). Three benefits result from this project. First, the scientific work is directed at a fundamental problem in regulation of gene expression, and the metamorphosis of insects in an easily accessible and fascinating model system for this study. Second, the practical implications of this work may lead to the development of new biologically specific and environmentally safer insect control strategies for crop pests. Third, the interdisciplinary training required for the students, postdoctoral fellow and faculty researchers involved enhances the quality and breadth of scientific inquiry in each laboratory.
这项由移动通信部门联合支持的拟议研究 生物科学和化学部,是一个 了解保幼激素作用的跨学科项目 在分子水平上结合化学学科, 分子生物学和生理学。 主要关键包括理解 基因表达的激素调节的分子基础 昆虫(L.M. Riddiford),JH的生化和分子研究 代谢与合成(B.D.吊床),并使用高特异性 活性标记的JH和JH(G.D. Prestwich)。 三个有利于 这个项目的结果。 一是科学工作导向 基因表达调控中的一个基本问题, 昆虫的变态在一个容易获得和迷人的 本研究的模型系统。 第二,实际影响 这项工作可能会导致新的生物学的发展, 具体和环境上更安全的昆虫控制战略, 农作物害虫 第三,跨学科培训需要 参与的学生、博士后研究员和教师研究人员 提高科学探究的质量和广度, 实验室
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Bruce Hammock其他文献
Methyl and phenyl esters and thioesters of carboxylic acids as surrogate substrates for microassay of proteinase K esterase activity
- DOI:
10.1007/s0021663540490 - 发表时间:
1996-02-01 - 期刊:
- 影响因子:3.800
- 作者:
Babak Borhan;Bruce Hammock;J. Seifert;Barry W. Wilson - 通讯作者:
Barry W. Wilson
<em>Drosophila</em> Pro-apoptotic Bcl-2/Bax Homologue Reveals Evolutionary Conservation of Cell Death Mechanisms
- DOI:
10.1016/s0021-9258(19)61510-3 - 发表时间:
2000-09-01 - 期刊:
- 影响因子:
- 作者:
Hong Zhang;Qihong Huang;Ning Ke;Shigemi Matsuyama;Bruce Hammock;Adam Godzik;John C. Reed - 通讯作者:
John C. Reed
Computational design of peptides to target Na<sub>v</sub>1.7 channel with high potency and selectivity for the treatment of pain
- DOI:
10.1016/j.bpj.2022.11.1739 - 发表时间:
2023-02-10 - 期刊:
- 影响因子:
- 作者:
Phuong T. Nguyen;Hai M. Nguyen;Karen M. Wagner;Robert Stewart;Vikrant Singh;Parashar Thapa;Anh Tuan Ton;Richard P. Kondo;Andre Ghetti;Michael W. Pennington;Bruce Hammock;Theanne N. Griffith;Jon T. Sack;Heike Wulff;Vladimir Yarov-Yarovoy - 通讯作者:
Vladimir Yarov-Yarovoy
Effect of soluble epoxide hydrolase and cyclooxygenase inhibition on lameness and synovial fluid prostanoids in horses with experimentally induced radiocarpal synovitis
- DOI:
10.1016/j.vaa.2018.09.015 - 发表时间:
2018-11-01 - 期刊:
- 影响因子:
- 作者:
Alonso Guedes;Troy Trumble;Laura Tucker;Caroline Baldo;Erin Wendt-Hornickle;Sung-Hee Hwang;Christophe Morisseau;Bruce Hammock - 通讯作者:
Bruce Hammock
Enhanced nanobody-driven bioluminescent immunoassay for rapid parathion detection using engineered split-nanoluciferase
- DOI:
10.1016/j.bios.2024.116913 - 发表时间:
2025-02-01 - 期刊:
- 影响因子:
- 作者:
Yi-Fan Liang;Qiu-Yue Pan;Yu Wang;Zhen-Lin Xu;Yu-Dong Shen;Jin-Yi Yang;Hiroshi Ueda;Bruce Hammock;Yuan-Ming Sun;Hong Wang - 通讯作者:
Hong Wang
Bruce Hammock的其他文献
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{{ truncateString('Bruce Hammock', 18)}}的其他基金
Specific Degradation of Juvenile Hormone Esterase
保幼激素酯酶的特异性降解
- 批准号:
9602893 - 财政年份:1997
- 资助金额:
$ 21万 - 项目类别:
Standard Grant
Collaborative Project: Receptors for Juvenile Hormones and JH Mimics
合作项目:保幼激素受体和 JH Mimics
- 批准号:
8818875 - 财政年份:1988
- 资助金额:
$ 21万 - 项目类别:
Continuing Grant
U.S.-Spain Program: Chemical and Biochemical Studies in Cytotoxic Epoxides
美国-西班牙项目:细胞毒性环氧化物的化学和生化研究
- 批准号:
8700736 - 财政年份:1988
- 资助金额:
$ 21万 - 项目类别:
Standard Grant
Receptors for Juvenile Hormones: Molecular Biology, Biochemistry, and Chemistry
保幼激素受体:分子生物学、生物化学和化学
- 批准号:
8518697 - 财政年份:1985
- 资助金额:
$ 21万 - 项目类别:
Continuing Grant
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