Purchase of a Superconducting Fourier Transform NMR System

购买超导傅里叶变换核磁共振系统

• 批准号: 9121380
• 负责人: Daniel Comins
• 金额: $ 13.83万
• 依托单位: North Carolina State University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1992
• 资助国家: 美国
• 起止时间: 1992-02-01 至 1993-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9121380&HistoricalAwards=false
• 关键词: Purchase; Superconducting; Fourier; Transform; NMR

This award from the Chemistry Research Instrumentation Program will help the Department of Chemistry at North Carolina State University acquire a 300 MHz NMR spectrometer which will be used in research investigations in the following areas of chemistry: (1) The synthesis of natural products and biologically active compounds using chiral auxiliary mediated asymmetric synthesis; (2) The generation and reactions of nucleophilic capped 1,3-dipole equivalents to carbonyl ylides; (3) The competition between electron donation and withdrawal in fluoro- and methoxyketones; (4) Theoretical and synthetic aspects of the rapidly expanding field of organofluorine chemistry; (5) The incorporation of fluorine atoms into organic molecules by devising new approaches to synthesize selectively fluorinated organic compounds; (6) Organo-analytical chemistry. Nuclear Magnetic Resonance (NMR) Spectroscopy is the most powerful tool available to the chemist for the elucidation of the structure of molecules. It is used to identify unknown substances, characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectroscopy is essential to chemists who are carrying out frontier research. The results from these NMR studies are useful in areas such as polymers and catalysis, and in biology.

化学研究仪器计划的这个奖项 将帮助北卡罗来纳州的化学系 大学获得300 MHz NMR光谱仪， 用于以下领域的研究调查： 化学： (1)天然产物的合成和生物 使用手性助剂介导的活性化合物 不对称合成; (2)亲核封端聚合物的生成和反应 羰基叶立德的1，3-偶极当量; (3)电子给予与电子撤回的竞争 氟酮和甲氧基酮; (4)理论和合成方面的快速 拓展有机氟化学领域; (5)氟原子与有机物的结合 通过设计新的方法来合成 选择性氟化的有机化合物; (6)有机分析化学 核磁共振（NMR）光谱是最 化学家可以用来阐明 分子的结构 它用于识别未知 物质，表征内部原子的特定排列 分子，并研究相互作用的动力学之间 溶液中的分子。 获得最先进的NMR 光谱学对化学家来说是必不可少的， 前沿研究 这些NMR研究的结果是 可用于聚合物和催化以及生物学等领域。