Use of FT-NMR Spectroscopy in the Undergraduate Chemistry Curriculum

傅立叶变换核磁共振波谱学在本科化学课程中的应用

• 批准号: 9151744
• 负责人: Robert Pinnell
• 金额: $ 8.27万
• 依托单位: Claremont McKenna College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-09-01 至 1994-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9151744&HistoricalAwards=false
• 关键词: Use; FT; NMR; Spectroscopy; Undergraduate

This project will introduce the capabilities of 200 MHz Fourier transform nuclear magnetic resonance (FT-NMR) spectroscopy into our courses in organic chemistry and advanced experimental techniques. In organic chemistry the instrument will be used for structural analyses via proton and carbon-13 spectroscopy. The greater sensitivity of FT-NMR to characterize products will find use in the microscale organic laboratory. Experiments will be introduced to increase student awareness of NMR applications. The high magnetic field and chemical shift reagents will be utilized to resolve spectra of complex molecules and optical stereoisomer mixtures. In the advanced course a variety of experiments will be offered which illustrate and explain currently used NMR techniques such as nuclear spin decoupling and measurement of nuclear relaxation times within a molecular structure. Reactions of organic ligands in transition metal coordination compounds will be monitored via carbon-13 observation.

这个项目将把200 MHz傅里叶变换核磁共振(FT-核磁共振)波谱的能力引入我们的有机化学和高级实验技术课程。在有机化学中，该仪器将用于通过质子和碳-13光谱进行结构分析。傅立叶变换核磁共振表征产物的更高灵敏度将在微型有机实验室中找到用武之地。将引入实验，以提高学生对核磁共振应用的认识。强磁场和化学位移试剂将被用来解析复杂分子和光学立体异构体混合物的光谱。在高级课程中，将提供各种实验来说明和解释当前使用的核磁共振技术，如核自旋去耦合和测量分子结构内的核弛豫时间。有机配体在过渡金属配位化合物中的反应将通过碳-13观察进行监测。