Computer-Assisted Chemical Analysis

该项目属于分析和表面化学的一般领域，以及分析质谱学的子领域。在这项为期三年的持续资助期间，威尔金斯教授和他的学生将扩展和扩大傅里叶变换质谱学(FTMS)应用方面的研究，这些研究是在美国国家科学基金会CHE-8911685资助下发起的。将研究基质辅助激光解吸(MALD)和表面诱导解离(SID)形成分析物离子，以便随后用FTMS进行表征。威尔金斯教授还将继续开发耦合气相色谱、红外光谱和质谱分析作为分析复杂混合物的灵敏工具。此外，他还将研究超临界流体色谱(SFC)和FTMS组合技术的分析能力。%这项研究继续开发适用于多种化学体系的强大分析技术。

This project is in the general area of analytical and surface chemistry and in the subfield of analytical mass spectrometry. During the tenure of this three-year continuing grant, Professor Wilkins and his students will extend and expand investigations in applications of Fourier transform mass spectrometry (FTMS) that were initiated under the aegis of NSF grant CHE-8911685. Analyte ion formation by both matrix assisted laser desorption (MALD) and by surface induced dissociation (SID) for subsequent characterization by FTMS will be studied. Professor Wilkins will also continue the development of coupled gas chromatography, infrared spectrometry, and mass spectrometry as a sensitive tool for the analysis of complex mixtures. Additionally, he will investigate the analytical capabilities of the combined techniques of supercritical fluid chromatography (SFC) and FTMS. %%% This research continues the development of powerful analytical techniques that are applicable to a broad array of chemical systems.