Polymer Analysis by Laser Desorption Fourier Transform Mass Spectrometry

这项名为“激光解吸傅里叶变换质谱学聚合物分析”的研究项目由阿肯色大学的查尔斯·威尔金斯博士执行，并得到化学部分析和表面化学项目的支持。本研究旨在建立基质辅助激光解吸电离(MALDI)傅立叶变换质谱仪(FTMS)分析聚合物和共聚物的新方法。将对阳离子的机理和基本的MALDI工艺进行基础研究。此外，还将对新发现的利用低电压开共振离子选择(LOIS)的离子活化过程进行额外的基础研究。通过这些基础研究开发的分析方法将应用于聚合物和共聚材料的表征。这项研究既是对影响聚合物分析的电离过程的基本理解的进展，也是对开发分析非常困难的聚合物材料的新方法的应用的进展。这项研究将对未来仪器的设计、性能和操作产生影响，并可能为重要工业材料的分析提供一种有用的方法。

The research program entitled "Polymer Analysis by Laser Desorption Fourier Transform Mass Spectrometry" is performed by Dr. Charles Wilkins at the University of Arkansas and is supported by the Analytical and Surface Chemistry Program of the Chemistry Division. The purpose of this research is to develop new methodologies for the analysis of polymers and copolymers by matrix assisted laser desorption/ionization (MALDI) Fourier transform mass spectrometry (FTMS). Fundamental studies on the mechanism of cationization and basic MALDI processes will be performed. Additional fundamental studies on the newly discovered ion activation process, which utilizes low voltage on-resonance ion selection (LOIS), will also be made. The analytical procedures developed as a result of these fundamental studies will be applied to the characterization of polymer and copolymer materials.This research represents advances in both the fundamental understanding of ionization processes as they affect polymer analysis and the application of this understanding to the development of new methods for the analysis of polymer materials, which are very difficult to analyze. This research will impact future instrument design, performance and operation and could provide a useful method for the analysis of industrially important materials.