Sterically Hindered Ligands and Studies of Their Biomimetic Metal Complexes

本研究将集中于阻碍双齿配体的合成，旨在增强金属（铜）周围的不寻常配位数和/或几何形状。这项工作旨在为理解金属蛋白（如azurin）的化学和光谱特性提供更好的模型。有了这个RUI奖，合成有机项目正在支持圣地亚哥大学化学系Patricia S. Traylor博士的研究。研究的重点将是使用阻碍配体来帮助理解重要金属酶类的特殊光谱和性质，并使本科生参与有意义的研究经验。

This research will focus on the synthesis of hindered bidentate ligands designed to enforce unusual coordination numbers and/or geometries around a metal (copper). The work seeks to provide better models for understanding the chemical and spectroscopic properties of metalloproteins such as azurin. %%% With this RUI award, the Synthetic Organic Program is supporting the research of Dr. Patricia S. Traylor of the Department of Chemistry at the University of San Diego. The focus of the research will be to use hindered ligands to help understand the extraordinary spectra and properties of important classes of metalloenzymes and to involve undergraduates in a meaningful research experience.