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Workshop on: "Molecular Biology of Mitochondrial Transport System; Ostuni, Italy, September 30 - October 3, 1992.

Workshop on: "Molecular Biology of Mitochondrial Transport System; Ostuni, Italy, September 30 - October 3, 1992.
研讨会:“线粒体运输系统的分子生物学;意大利奥斯图尼,1992 年 9 月 30 日至 10 月 3 日。
批准号:
9211759
负责人:
Michael Forte
金额:
$0.72万
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
1992
资助国家:
美国
项目状态:
已结题
起止时间:
1992-07-01 至 1993-12-31

项目摘要

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中文摘要
翻译
绝大多数真核细胞含有许多线粒体。 在这个细胞器中,小分子的氧化产生 细胞ATP,从而提供大部分可用的能量, cell. 线粒体和相关细胞内的一个独特特征 细胞器是由两个独立的, 相互作用的膜系统。 嵌入在这两个 膜是各种通道和载体分子, 负责巨大的生物化学任务, 这种结构;高电荷分子的运输到 从线粒体中分离出来。 许多负责的分子 已经确定了这些运输过程, 近几个月来的特点。 该领域的许多最新进展是由以下方面取得的: 调查人员应用不同的技术和方法。 这次研讨会的主题是“线粒体转运的分子生物学 系统”将汇集科学家研究这些系统, 开始识别结构相似性的不同方法 和功能上重要的相互作用。 尽管许多 个体玩家是已知的,潜在功能的性质 相互作用和保守的结构基序还有待于 彻底探索。 这是一个重要的和及时的, 一个多学科的研究小组 线粒体转运系统的不同方法,但与 同样的总体目标。
英文摘要
The vast majority of eukaryotic cells contain many mitochondria. In this organelle, the oxidation of small molecules generates cellular ATP, thus providing most of the available energy for the cell. A unique feature of mitochondria and related intracellular organelles is that they are composed of two independent yet interacting membrane systems. Embedded in both of these membranes are a variety of channel and carrier molecules that are responsible for the monumental biochemical tasks necessitated by this structure; the transport of highly charged molecules into and out of the mitochondria. Many of the molecules responsible for these transport processes have been identified and characterized in recent months. Many of the recent advances in the field have been made by investigators applying disparate technologies and methodologies. This workshop on "Molecular Biology of Mitochondrial Transport System" will bring together scientists examining these systems by different approaches to begin to identify structural similarities and functionally important interactions. Although many of the individual players are known, the nature of potential functional interactions and conserved structural motifs have yet to be thoroughly explored. It is both important and timely to bring together a multidisciplinary group of investigators examining mitochondrial transport systems by different approaches but with the same overall goal.
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