U.S.-Australia Cooperative Research: Algal Virus RestrictionModification Enzymes

这个奖项支持詹姆斯货车博士的旅行 内布拉斯加大学林肯分校的埃滕 澳大利亚进行合作研究 研究学院的Jan Rohozinski博士 澳大利亚生物科学学院 国立大学。研究的目标 就是了解DNA的生物学功能 甲基转移酶和DNA限制酶 由感染真核生物的病毒编码。 藻类病毒是二十面体DNA， 病毒感染的细胞。 具体来说，该研究将试图 建立一个转基因系统 这样藻类病毒基因的研究就可以 进行。 开发转换系统的工作是 在澳大利亚的澳大利亚 堪培拉的国立大学。一旦 建立了转换系统， 将完成病毒基因的克隆。 内布拉斯加大学的设施 被认为是研究 这些病毒和限制性修饰 系统编码。的分析 限制性修饰基因，由 澳大利亚调查人员将在 内布拉斯加大学

This award supports the travel of Dr. James Van Etten of the University of Nebraska at Lincoln to Australia to conduct collaborative research with Dr. Jan Rohozinski of the Research School of Biological Sciences at the Australian National University. The goal of the research is to understand the biological function of DNA methyltransferases and DNA restriction enzymes coded by viruses which infect eukaryotic alga. Algal viruses are icosahedral DNA containing viruses which infect chlorella cells. Specifically, the research will attempt to establish a transformation system in chlorella so that studies of algal viral genes can be undertaken. Work to develop the transformation system is to be carried out in Australia at the Australian National University in Canberra. Once the transformation system is established, the cloning of viral genes will be accomplished. The facilities at the University of Nebraska are recognized as a major center for studying these viruses and the restriction modification system they encode. The analysis of the restriction modification genes, isolated by the Australian investigators, will be done at the University of Nebraska.