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Regulation of germline stem cell quiescence through small RNA-mediated chromatin remodeling

Regulation of germline stem cell quiescence through small RNA-mediated chromatin remodeling
通过小RNA介导的染色质重塑调节生殖干细胞静止
批准号:
451020
负责人:
Roy Richard D
金额:
$52.11万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2021
资助国家:
加拿大
项目状态:
未结题
起止时间:
2021-09-01 至 2026-09-01

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中文摘要
翻译
干细胞对于我们许多组织的生长和维持非常重要。奇怪的是,它们不喜欢分裂,只有当信号指示它们修复损伤或出于某种原因制造新组织时,它们才会分裂。如果这些细胞失去了
英文摘要
Stem cells are very important for the growth and maintenance of a number of our tissues. Curiously, they do not like to divide and only do so when signals instruct them to repair damage or, for whatever reason, to make new tissue. If these cells lose the
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AMPK blocks epigenetic misregulation and genome instability following acute starvation in C. elegans
  • 批准号:
    409364
  • 项目类别:
    Operating Grants
  • 资助金额:
    $49.04万
  • 财政年份:
    2019
  • 负责人:
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  • 依托单位:
AMPK-dependent regulation of epigenetic modification links physiology to stem cell integrity
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  • 财政年份:
    2016
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Downstream effectors of LKB1 mediated tumour suppression
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    344424
  • 项目类别:
    Operating Grants
  • 资助金额:
    $18.1万
  • 财政年份:
    2016
  • 负责人:
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  • 依托单位:
Dissecting the mechanisms required to regulate metabolism and tumour growth downstream of LKB1/AMPK signalling.
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    200008
  • 项目类别:
    Operating Grants
  • 资助金额:
    $43.54万
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  • 负责人:
    Roy Richard D
  • 依托单位:
海外基金