Endocrine Regulation of Sex Phermone Production in the Housefly

这项拟议工作的目标是详细了解来自卵巢的产品在普通家蝇中启动性信息素产生的生化过程。家蝇性信息素是雌性为了吸引雄性交配而产生的一种化学引诱剂。要利用昆虫这种化学交流的基本形式，需要对性信息素的产生有更好的了解。昆虫性信息素的产生是通过鳞翅目的大脑因素、蟑螂和甲虫的保幼激素、家蝇的蜕皮类固醇以及其他双翅目昆虫的蜕皮激素来调节的。在这些系统中，没有一个清楚地了解哪些酶的活动会影响控制性信息素的产生。这项工作的目的是为了更清楚地了解蜕皮激素对导致性信息素产生的酶的影响，并为基于抑制性信息素产生的昆虫控制策略提供必要的基本信息。

The goal of the proposed work is to gain a detailed understanding of the biochemical processes by which a product from the ovary initiates sex pheromone production in the common housefly. The housefly sex pheromone is a chemical attractant produced by the female to attract males for mating. A better understanding of sex pheromone production is needed to take advantage of this essential form of chemical communication in insects. The regulation of sex pheromone production in insects occurs via a brain factor in Lepidoptera, by juvenile hormones in cockroaches and beetles and by ecdysteroids in the housefly and perhaps in other Diptera. In none of these systems is it clearly understood which enzyme activities are affected to control sex pheromone production. The work proposed here is designed to gain a clear understanding of the enzymes influenced by ecdysone which result in sex pheromone production and to provide the basic information necessary to develop insect control strategies based on inhibiting sex pheromone production.