Collaborative Research: Abiotic Stress Combination: Bridging the gap between Arabidopsis Stress Research and Agriculture

拟南芥2010：非生物胁迫组合：弥合拟南芥逆境研究和农业之间的差距在这个项目上进行的工作旨在为2010年计划的目标做出重大贡献-了解拟南芥中每个基因的网络和功能。该项目的具体重点是非生物压力组合以及对干旱和高温、干旱和盐碱以及盐碱和高温等压力组合作出反应的遗传和代谢网络。非生物胁迫是世界范围内作物损失的主要原因，美国每年的损失估计为140 - 190亿美元。虽然非生物胁迫通常通过施加单一胁迫条件如干旱、盐度或热在拟南芥中进行研究，但这种类型的分析并不反映作物植物经受不同胁迫组合的田间发生的条件。该项目的中心目标是确定新的基因，基因网络和代谢途径，特别是对两种不同的非生物胁迫的组合作出反应。有待检验的假设是，在同时暴露于两种不同胁迫条件的植物中，专用基因、网络和途径被激活。该项目旨在将拟南芥引入非生物胁迫耐受性应用研究的前沿，并弥合实验室中对拟南芥进行的胁迫研究与田间影响作物的条件之间的差距。拟议研究的两个关键“更广泛的影响”是：1）开发和维护一个集中的网站，将农学家，育种家和拟南芥分子生物学家（http：//www.ag.unr.edu/Stress_Combination/）。2)为K-12和博士后、研究生和本科生学员提供多学科培训的教育推广。本科生和K-12外展和培训活动都将针对科学领域的弱势群体。从历史上看，非生物胁迫组合，如干旱和高温，对美国产生了最具破坏性的经济和社会影响，1980年和1988年分别损失了484亿美元和616亿美元。拟议的项目将为开发具有更强的非生物胁迫耐受性的作物铺平道路，有助于减轻未来天气灾害的后果，由于预期的气候变化，天气灾害可能会增加频率。

Arabidopsis 2010: Abiotic stress combination: Bridging the gap between Arabidopsis stress research and agricultureThe work undertaken on this project is designed to make significant contributions to the goals of the 2010 program - to understand the networking and function of every gene in Arabidopsis. The specific focus of the project is on abiotic stress combinations and the genetic and metabolic networks that respond to stress combinations such as drought and heat, drought and salinity and salinity and heat. Abiotic stress is the primary cause of crop loss world-wide, with losses in the US estimated at 14-19 billion dollars each year. While abiotic stress is routinely studied in Arabidopsis by applying a single stress condition such as drought, salinity or heat, this type of analysis does not reflect the conditions that occur in the field where crop plants are subjected to a combination of different stresses. The central objective of the project is to identify novel genes, gene networks and metabolic pathways that specifically respond to a combination of two different abiotic stresses. The hypothesis to be tested is that dedicated genes, networks and pathways are activated in plants that are simultaneously exposed to two different stress conditions. This project is designed to bring Arabidopsis into the front line of applied research on abiotic stress tolerance, and bridge the gap between stress studies conducted with Arabidopsis in the lab and the conditions that impact crops in the field. The two key "Broader Impacts" of the proposed research are: 1) Development and maintenance of a centralized website that will bring together agronomists, breeders and Arabidopsis molecular biologists (http://www.ag.unr.edu/Stress_Combination/). 2) Educational outreach for K-12 and multidisciplinary training to postdoctoral, graduate and undergraduates trainees. Both undergraduate and K-12 outreach and training activities will target the under privileged and under represented in Science. Historically, abiotic stress combinations, such as drought and heat, had the outmost devastating economical and sociological impacts on the US, with losses of 48.4 and 61.6 billion dollars in 1980 and 1988 respectively. The proposed project will pave the way for the development of crops with enhanced abiotic stress tolerance, contributing to ameliorate the consequences of future weather disasters that are likely to increase in frequency due to anticipated climatic changes.